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Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats

Pancreatic β-cells have an extraordinary ability to adapt to acute fluctuations in glucose levels by rapid changing insulin production to meet metabolic needs. Although acute changes have been characterised, effects of prolonged metabolic stress on β-cell dynamics are still unclear. Here, the aim wa...

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Detalles Bibliográficos
Autores principales:	Jensen, Vivi F. H., Mølck, Anne-Marie, Nowak, Jette, Fels, Johannes J., Lykkesfeldt, Jens, Bøgh, Ingrid B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388517/ https://www.ncbi.nlm.nih.gov/pubmed/35982111 http://dx.doi.org/10.1038/s41598-022-18398-z

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