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Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed

There are various interventions of rehabilitation on the bed, but these are time-consuming and cannot be performed for all patients. The purpose of this study was to identify the patients who require early mobilization based on the level of sedation. We retrospectively evaluated the data of patients...

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Autores principales: Morimoto, Yosuke, Watanabe, Tsubasa, Oikawa, Masato, Hanada, Masatoshi, Sekino, Motohiro, Hara, Tetsuya, Kozu, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388676/
https://www.ncbi.nlm.nih.gov/pubmed/35982206
http://dx.doi.org/10.1038/s41598-022-18311-8
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author Morimoto, Yosuke
Watanabe, Tsubasa
Oikawa, Masato
Hanada, Masatoshi
Sekino, Motohiro
Hara, Tetsuya
Kozu, Ryo
author_facet Morimoto, Yosuke
Watanabe, Tsubasa
Oikawa, Masato
Hanada, Masatoshi
Sekino, Motohiro
Hara, Tetsuya
Kozu, Ryo
author_sort Morimoto, Yosuke
collection PubMed
description There are various interventions of rehabilitation on the bed, but these are time-consuming and cannot be performed for all patients. The purpose of this study was to identify the patients who require early mobilization based on the level of sedation. We retrospectively evaluated the data of patients who underwent physical therapy, ICU admission of > 48 h, and were discharged alive. Sedation was defined as using sedative drugs and a Richmond Agitation–Sedation Scale score of < − 2. Multiple regression analysis was performed using sedation period as the objective variable, and receiver operating characteristic (ROC) curve and Spearman’s rank correlation coefficient were performed. Of 462 patients admitted to the ICU, the data of 138 patients were analyzed. The Sequential Organ Failure Assessment (SOFA) score and non-surgery and emergency surgery cases were extracted as significant factors. The ROC curve with a positive sedation period of more than 3 days revealed the SOFA cutoff score was 10. A significant positive correlation was found between sedation period and the initial day on early mobilization. High SOFA scores, non-surgery and emergency surgery cases may be indicators of early mobilization on the bed in the ICU.
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spelling pubmed-93886762022-08-20 Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed Morimoto, Yosuke Watanabe, Tsubasa Oikawa, Masato Hanada, Masatoshi Sekino, Motohiro Hara, Tetsuya Kozu, Ryo Sci Rep Article There are various interventions of rehabilitation on the bed, but these are time-consuming and cannot be performed for all patients. The purpose of this study was to identify the patients who require early mobilization based on the level of sedation. We retrospectively evaluated the data of patients who underwent physical therapy, ICU admission of > 48 h, and were discharged alive. Sedation was defined as using sedative drugs and a Richmond Agitation–Sedation Scale score of < − 2. Multiple regression analysis was performed using sedation period as the objective variable, and receiver operating characteristic (ROC) curve and Spearman’s rank correlation coefficient were performed. Of 462 patients admitted to the ICU, the data of 138 patients were analyzed. The Sequential Organ Failure Assessment (SOFA) score and non-surgery and emergency surgery cases were extracted as significant factors. The ROC curve with a positive sedation period of more than 3 days revealed the SOFA cutoff score was 10. A significant positive correlation was found between sedation period and the initial day on early mobilization. High SOFA scores, non-surgery and emergency surgery cases may be indicators of early mobilization on the bed in the ICU. Nature Publishing Group UK 2022-08-18 /pmc/articles/PMC9388676/ /pubmed/35982206 http://dx.doi.org/10.1038/s41598-022-18311-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Morimoto, Yosuke
Watanabe, Tsubasa
Oikawa, Masato
Hanada, Masatoshi
Sekino, Motohiro
Hara, Tetsuya
Kozu, Ryo
Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title_full Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title_fullStr Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title_full_unstemmed Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title_short Predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
title_sort predictors of sedation period for critical illness patients focusing on early rehabilitation on the bed
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388676/
https://www.ncbi.nlm.nih.gov/pubmed/35982206
http://dx.doi.org/10.1038/s41598-022-18311-8
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