Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications

Numerous genes exert multifaceted roles in hematopoiesis. Therefore, we generated novel lineage-specific RNA interference (RNAi) lentiviral vectors, H23B-Ery-Lin-shRNA and H234B-Ery-Lin-shRNA, to probe the functions of these genes in erythroid cells without affecting other hematopoietic lineages. Th...

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Detalles Bibliográficos
Autores principales: Bagchi, Abhirup, Devaraju, Nivedhitha, Chambayil, Karthik, Rajendiran, Vignesh, Venkatesan, Vigneshwaran, Sayed, Nilofer, Pai, Aswin Anand, Nath, Aneesha, David, Ernest, Nakamura, Yukio, Balasubramanian, Poonkuzhali, Srivastava, Alok, Thangavel, Saravanabhavan, Mohankumar, Kumarasamypet M., Velayudhan, Shaji R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388678/
https://www.ncbi.nlm.nih.gov/pubmed/35982069
http://dx.doi.org/10.1038/s41598-022-13783-0

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