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Efficient engraftment and viral transduction of human hepatocytes in an FRG rat liver humanization model

Humanized liver rodent models, in which the host liver parenchyma is repopulated by human hepatocytes, have been increasingly used for drug development and disease research. Unlike the leading humanized liver mouse model in which Fumarylacetoacetate Hydrolase (Fah), Recombination Activating Gene (Ra...

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Detalles Bibliográficos
Autores principales:	Carbonaro, Marisa, Lee, Jeffrey, Pefanis, Evangelos, Desclaux, Mathieu, Wang, Kehui, Pennington, Alexander, Huang, Hui, Mujica, Alejo, Rojas, Jose, Ally, Roxanne, Kennedy, Daniel, Brown, Michael, Rogulin, Vitaliy, Moller-Tank, Sven, Sabin, Leah, Zambrowicz, Brian, Thurston, Gavin, Li, Zhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388686/ https://www.ncbi.nlm.nih.gov/pubmed/35982097 http://dx.doi.org/10.1038/s41598-022-18119-6

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