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Proton pump inhibitors and sensitization of cancer cells to radiation therapy

This review article outlines six molecular pathways that confer resistance of cancer cells to ionizing radiation, and describes how proton pump inhibitors (PPIs) may be used to overcome radioresistance induced by alteration of one or more of these signaling pathways. The inflammatory, adaptive, hypo...

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Detalles Bibliográficos
Autores principales: Hebert, Kassidy A., Bonnen, Mark D., Ghebre, Yohannes T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388769/
https://www.ncbi.nlm.nih.gov/pubmed/35992826
http://dx.doi.org/10.3389/fonc.2022.937166