Glucose controls co-translation of structurally related mRNAs via the mTOR and eIF2 pathways in human pancreatic beta cells

Pancreatic beta cell response to glucose is critical for the maintenance of normoglycemia. A strong transcriptional response was classically described in rodent models but, interestingly, not in human cells. In this study, we exposed human pancreatic beta cells to an increased concentration of gluco...

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Detalles Bibliográficos
Autores principales: Bulfoni, Manuel, Bouyioukos, Costas, Zakaria, Albatoul, Nigon, Fabienne, Rapone, Roberta, Del Maestro, Laurence, Ait-Si-Ali, Slimane, Scharfmann, Raphaël, Cosson, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388909/
https://www.ncbi.nlm.nih.gov/pubmed/35992129
http://dx.doi.org/10.3389/fendo.2022.949097

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