Cargando…

Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine

The chromatographic column is the core of a high-performance liquid chromatography (HPLC) system, and must have excellent separation efficiency and selectivity. Therefore, functional modification materials for monolithic columns have been rapidly developed. This study is a systematic review of the r...

Descripción completa

Detalles Bibliográficos
Autores principales: Si, Helong, Wang, Quan, Guo, Yuanyuan, Zhao, Yuxin, Li, Hongya, Li, Shuna, Wang, Shuxiang, Zhu, Baocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388943/
https://www.ncbi.nlm.nih.gov/pubmed/35991596
http://dx.doi.org/10.3389/fchem.2022.951649
_version_ 1784770325992439808
author Si, Helong
Wang, Quan
Guo, Yuanyuan
Zhao, Yuxin
Li, Hongya
Li, Shuna
Wang, Shuxiang
Zhu, Baocheng
author_facet Si, Helong
Wang, Quan
Guo, Yuanyuan
Zhao, Yuxin
Li, Hongya
Li, Shuna
Wang, Shuxiang
Zhu, Baocheng
author_sort Si, Helong
collection PubMed
description The chromatographic column is the core of a high-performance liquid chromatography (HPLC) system, and must have excellent separation efficiency and selectivity. Therefore, functional modification materials for monolithic columns have been rapidly developed. This study is a systematic review of the recently reported functionalized monolithic columns. In particular, the study reviews the types of functional monomers under different modification conditions, as well as the separation and detection techniques combined with chromatography, and their development prospects. In addition, the applications of functionalized monolithic columns in food analysis, biomedicine, and the analysis of active ingredient of Chinese herbal medicines in recent years are also discussed. Also reviewed are the functionalized monolithic columns for qualitative and quantitative analysis. It provided a reference for further development and application of organic polymer monolithic columns.
format Online
Article
Text
id pubmed-9388943
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-93889432022-08-20 Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine Si, Helong Wang, Quan Guo, Yuanyuan Zhao, Yuxin Li, Hongya Li, Shuna Wang, Shuxiang Zhu, Baocheng Front Chem Chemistry The chromatographic column is the core of a high-performance liquid chromatography (HPLC) system, and must have excellent separation efficiency and selectivity. Therefore, functional modification materials for monolithic columns have been rapidly developed. This study is a systematic review of the recently reported functionalized monolithic columns. In particular, the study reviews the types of functional monomers under different modification conditions, as well as the separation and detection techniques combined with chromatography, and their development prospects. In addition, the applications of functionalized monolithic columns in food analysis, biomedicine, and the analysis of active ingredient of Chinese herbal medicines in recent years are also discussed. Also reviewed are the functionalized monolithic columns for qualitative and quantitative analysis. It provided a reference for further development and application of organic polymer monolithic columns. Frontiers Media S.A. 2022-08-05 /pmc/articles/PMC9388943/ /pubmed/35991596 http://dx.doi.org/10.3389/fchem.2022.951649 Text en Copyright © 2022 Si, Wang, Guo, Zhao, Li, Li, Wang and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Si, Helong
Wang, Quan
Guo, Yuanyuan
Zhao, Yuxin
Li, Hongya
Li, Shuna
Wang, Shuxiang
Zhu, Baocheng
Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title_full Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title_fullStr Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title_full_unstemmed Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title_short Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
title_sort functionalized monolithic columns: recent advancements and their applications for high-efficiency separation and enrichment in food and medicine
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388943/
https://www.ncbi.nlm.nih.gov/pubmed/35991596
http://dx.doi.org/10.3389/fchem.2022.951649
work_keys_str_mv AT sihelong functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT wangquan functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT guoyuanyuan functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT zhaoyuxin functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT lihongya functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT lishuna functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT wangshuxiang functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine
AT zhubaocheng functionalizedmonolithiccolumnsrecentadvancementsandtheirapplicationsforhighefficiencyseparationandenrichmentinfoodandmedicine