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TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1–mediated epithelial to mesenchymal transition in nasal epithelial cells

Chronic rhinosinusitis with nasal polyps (CRSwNP) is caused by prolonged inflammation of the paranasal sinus mucosa. The epithelial to mesenchymal transition (EMT) is involved in the occurrence and development of CRSwNP. The T-cell immunoglobulin domain and the mucin domain 4 (TIM-4) is closely rela...

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Detalles Bibliográficos
Autores principales:	Qin, Danxue, Liu, Peiqiang, Zhou, Huiqin, Jin, Jing, Gong, Wanyang, Liu, Kunyu, Chen, Siyuan, Huang, Jingyu, Fan, Wenjun, Tao, Zezhang, Xu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389014/ https://www.ncbi.nlm.nih.gov/pubmed/35990621 http://dx.doi.org/10.3389/fimmu.2022.941608

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