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Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review

BACKGROUND: The minimum clinically effective dose, and whether this is received in randomised controlled trials (RCTs) of complex self-management interventions in long-term conditions (LTCs), can be unclear. The Template for Intervention Description and Replication (TIDieR) checklist states that dos...

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Autores principales: Rookes, Tasmin Alanna, Barat, Atena, Turner, Rebecca, Taylor, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389087/
https://www.ncbi.nlm.nih.gov/pubmed/35977763
http://dx.doi.org/10.1136/bmjopen-2021-056532
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author Rookes, Tasmin Alanna
Barat, Atena
Turner, Rebecca
Taylor, Stephanie
author_facet Rookes, Tasmin Alanna
Barat, Atena
Turner, Rebecca
Taylor, Stephanie
author_sort Rookes, Tasmin Alanna
collection PubMed
description BACKGROUND: The minimum clinically effective dose, and whether this is received in randomised controlled trials (RCTs) of complex self-management interventions in long-term conditions (LTCs), can be unclear. The Template for Intervention Description and Replication (TIDieR) checklist states that dose should be clearly reported to ensure validity and reliable implementation. OBJECTIVES: To identify whether the expected minimum clinically effective dose, and the dose participants received is reported within research articles and if reporting has improved since the TIDieR checklist was published. METHODS: Four databases were systematically searched (MEDLINE, PsycINFO, AMED and CINAHL) to identify published reports between 2008 and 2022 for RCTs investigating complex self-management interventions in LTCs. Data on reporting of dose were extracted and synthesised from the eligible articles. RESULTS: 94 articles covering various LTCs including diabetes, stroke and arthritis were included. Most complex interventions involved behaviour change combined with education and/or exercise. The maximum dose was usually reported (n=90; 97.8%), but the expected minimum clinically effective dose and the dose received were reported in only 28 (30.4%) and 62 (67.4%) articles, respectively. Reporting of the expected minimum clinically effective dose and the dose participants received did not improve following the publication of the TIDieR checklist in 2014. CONCLUSIONS: Interpreting results and implementing effective complex self-management interventions is difficult when researchers’ reporting of dose is not in line with guidelines. If trial findings indicate benefit from the intervention, clear reporting of dose ensures reliable implementation to standard care. If the results are non-significant, detailed reporting enables better interpretation of results, that is, differentiating between poor implementation and lack of effectiveness. This ensures quality of interventions and validity and generalisability of trial findings. Therefore, wider adoption of reporting the TIDieR checklist dose aspects is strongly recommended. Alternatively, customised guidelines for reporting dose in complex self-management interventions could be developed. PROSPERO REGISTRATION NUMBER: CRD42020180988.
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spelling pubmed-93890872022-09-06 Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review Rookes, Tasmin Alanna Barat, Atena Turner, Rebecca Taylor, Stephanie BMJ Open Evidence Based Practice BACKGROUND: The minimum clinically effective dose, and whether this is received in randomised controlled trials (RCTs) of complex self-management interventions in long-term conditions (LTCs), can be unclear. The Template for Intervention Description and Replication (TIDieR) checklist states that dose should be clearly reported to ensure validity and reliable implementation. OBJECTIVES: To identify whether the expected minimum clinically effective dose, and the dose participants received is reported within research articles and if reporting has improved since the TIDieR checklist was published. METHODS: Four databases were systematically searched (MEDLINE, PsycINFO, AMED and CINAHL) to identify published reports between 2008 and 2022 for RCTs investigating complex self-management interventions in LTCs. Data on reporting of dose were extracted and synthesised from the eligible articles. RESULTS: 94 articles covering various LTCs including diabetes, stroke and arthritis were included. Most complex interventions involved behaviour change combined with education and/or exercise. The maximum dose was usually reported (n=90; 97.8%), but the expected minimum clinically effective dose and the dose received were reported in only 28 (30.4%) and 62 (67.4%) articles, respectively. Reporting of the expected minimum clinically effective dose and the dose participants received did not improve following the publication of the TIDieR checklist in 2014. CONCLUSIONS: Interpreting results and implementing effective complex self-management interventions is difficult when researchers’ reporting of dose is not in line with guidelines. If trial findings indicate benefit from the intervention, clear reporting of dose ensures reliable implementation to standard care. If the results are non-significant, detailed reporting enables better interpretation of results, that is, differentiating between poor implementation and lack of effectiveness. This ensures quality of interventions and validity and generalisability of trial findings. Therefore, wider adoption of reporting the TIDieR checklist dose aspects is strongly recommended. Alternatively, customised guidelines for reporting dose in complex self-management interventions could be developed. PROSPERO REGISTRATION NUMBER: CRD42020180988. BMJ Publishing Group 2022-08-17 /pmc/articles/PMC9389087/ /pubmed/35977763 http://dx.doi.org/10.1136/bmjopen-2021-056532 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Evidence Based Practice
Rookes, Tasmin Alanna
Barat, Atena
Turner, Rebecca
Taylor, Stephanie
Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title_full Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title_fullStr Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title_full_unstemmed Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title_short Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
title_sort reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? a systematic review
topic Evidence Based Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389087/
https://www.ncbi.nlm.nih.gov/pubmed/35977763
http://dx.doi.org/10.1136/bmjopen-2021-056532
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