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TET proteins regulate T cell and iNKT cell lineage specification in a TET2 catalytic dependent manner

TET proteins mediate DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC) and other oxidative derivatives. We have previously demonstrated a dynamic enrichment of 5hmC during T and invariant natural killer T cell lineage specification. Here, we investigate shared signatu...

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Detalles Bibliográficos
Autores principales: Äijö, Tarmo, Theofilatos, Dimitris, Cheng, Meng, Smith, Matthew D., Xiong, Yue, Baldwin, Albert S., Tsagaratou, Ageliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389146/
https://www.ncbi.nlm.nih.gov/pubmed/35990681
http://dx.doi.org/10.3389/fimmu.2022.940995