Cargando…

TET proteins regulate T cell and iNKT cell lineage specification in a TET2 catalytic dependent manner

TET proteins mediate DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC) and other oxidative derivatives. We have previously demonstrated a dynamic enrichment of 5hmC during T and invariant natural killer T cell lineage specification. Here, we investigate shared signatu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Äijö, Tarmo, Theofilatos, Dimitris, Cheng, Meng, Smith, Matthew D., Xiong, Yue, Baldwin, Albert S., Tsagaratou, Ageliki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389146/ https://www.ncbi.nlm.nih.gov/pubmed/35990681 http://dx.doi.org/10.3389/fimmu.2022.940995

Ejemplares similares

TET Methylcytosine Oxidases in T Cell and B Cell Development and Function
por: Tsagaratou, Ageliki, et al.
Publicado: (2017)

Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN
por: Theofilatos, Dimitris, et al.
Publicado: (2022)

TET Proteins in the Spotlight: Emerging Concepts of Epigenetic Regulation in T Cell Biology
por: Tsagaratou, Ageliki
Publicado: (2023)

Control of Foxp3 stability through modulation of TET activity
por: Yue, Xiaojing, et al.
Publicado: (2016)

TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease
por: Tsiouplis, Nikolas James, et al.
Publicado: (2021)

iNKT and MAIT Cell Alterations in Diabetes
por: Magalhaes, Isabelle, et al.
Publicado: (2015)

The Role of Autophagy in iNKT Cell Development
por: Yang, Guan, et al.
Publicado: (2018)

CD8(+) T-cell immunity orchestrated by iNKT cells
por: Qin, Yingyu, et al.
Publicado: (2023)

Enhancing Neuroblastoma Immunotherapies by Engaging iNKT and NK Cells
por: McNerney, Kevin O., et al.
Publicado: (2020)

New insights into iNKT cells and their roles in liver diseases
por: Gu, Xinyu, et al.
Publicado: (2022)

iNKT Cells and Their Potential Lipid Ligands during Viral Infection
por: Opasawatchai, Anunya, et al.
Publicado: (2015)

The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues
por: Cortesi, Filippo, et al.
Publicado: (2018)

Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
por: Cakouros, Dimitrios, et al.
Publicado: (2019)

Regulated Expression of miR-155 is Required for iNKT Cell Development
por: Burocchi, Alessia, et al.
Publicado: (2015)

How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets
por: Wang, Haiguang, et al.
Publicado: (2018)

Reduction of Peripheral Blood iNKT and γδT Cells in Patients With Parkinson's Disease: An Observational Study
por: Zhou, Chao, et al.
Publicado: (2020)

Differential Control of iNKT Cell Effector Lineage Differentiation by the Forkhead Box Protein O1 (Foxo1) Transcription Factor
por: Tao, Huishan, et al.
Publicado: (2019)

Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy
por: Wang, Ying, et al.
Publicado: (2019)

Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses
por: Stolk, Dorian A., et al.
Publicado: (2020)

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways
por: Äijö, Tarmo, et al.
Publicado: (2016)

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2019)

iNKT Cells in Secondary Progressive Multiple Sclerosis Patients Display Pro-inflammatory Profiles
por: De Biasi, Sara, et al.
Publicado: (2016)

α-GalCer and iNKT Cell-Based Cancer Immunotherapy: Realizing the Therapeutic Potentials
por: Zhang, Yingting, et al.
Publicado: (2019)

Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes
por: Look, Alex, et al.
Publicado: (2023)

Recent advances in iNKT cell development
por: Hogquist, Kristin, et al.
Publicado: (2020)

CCR7 defines a precursor for murine iNKT cells in thymus and periphery
por: Wang, Haiguang, et al.
Publicado: (2018)

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2020)

iNKT Cells Suppress Pathogenic NK1.1(+)CD8(+) T Cells in DSS-Induced Colitis
por: Lee, Sung Won, et al.
Publicado: (2018)

Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8(+) iNKT cells are depleted after peanut oil exposure
por: Hopkins, Georgina V., et al.
Publicado: (2023)

Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways
por: Bai, Shiyu, et al.
Publicado: (2023)

The “epiTet” of Air Pollution: Epigenetic Regulation of Airway Inflammation by Tet1
por: Ji, Hong, et al.
Publicado: (2023)

The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation
por: Won, Hee Yeun, et al.
Publicado: (2021)

Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model
por: Lee, Sung Won, et al.
Publicado: (2018)

Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy
por: Aoki, Takahiro, et al.
Publicado: (2023)

Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner
por: Jahnke, Simona, et al.
Publicado: (2019)

Hepatic iNKT cells produce type 2 cytokines and restrain antiviral T cells during acute hepacivirus infection
por: Raus, Svjetlana, et al.
Publicado: (2022)

CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma
por: Rowan, Aileen G., et al.
Publicado: (2023)

RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development
por: Hägglöf, Thomas, et al.
Publicado: (2023)

Loss of TET2 and TET3 in regulatory T cells unleashes effector function
por: Yue, Xiaojing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j5a47giocs7qagqt6mv8hck2c8