Cargando…

Network pharmacology and molecular docking-based investigations of Kochiae Fructus’s active phytomolecules, molecular targets, and pathways in treating COVID-19

COVID-19 disease is caused by SARS-CoV-2. Hyper-inflammation mediated by proinflammatory cytokines is humans’ primary etiology of SARS-CoV-2 infection. Kochiae Fructus is widely used in China as traditional Chinese medicine (TCM) to treat inflammatory diseases. Due to its anti-inflammatory propertie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Shakeel Ahmad, Lee, Terence Kin Wah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389148/ https://www.ncbi.nlm.nih.gov/pubmed/35992697 http://dx.doi.org/10.3389/fmicb.2022.972576

Ejemplares similares

Investigations of nitazoxanide molecular targets and pathways for the treatment of hepatocellular carcinoma using network pharmacology and molecular docking
por: Khan, Shakeel Ahmad, et al.
Publicado: (2022)

Kochiae Fructus, the Fruit of Common Potherb Kochia scoparia (L.) Schrad: A Review on Phytochemistry, Pharmacology, Toxicology, Quality Control, and Pharmacokinetics
por: Zou, Wei, et al.
Publicado: (2021)

Network pharmacology and molecular docking-based prediction of active compounds and mechanisms of action of Cnidii Fructus in treating atopic dermatitis
por: Khan, Shakeel Ahmad, et al.
Publicado: (2022)

Triterpenoids from Kochiae Fructus: Glucose Uptake in 3T3-L1 Adipocytes and α-Glucosidase Inhibition, In Silico Molecular Docking
por: Chen, Xue-Lin, et al.
Publicado: (2023)

Network-Pharmacology-Based Study on Active Phytochemicals and Molecular Mechanism of Cnidium monnieri in Treating Hepatocellular Carcinoma
por: Khan, Shakeel Ahmad, et al.
Publicado: (2022)

Identifying potential pharmacological targets and molecular pathways of Meliae cortex for COVID-19 therapy
por: Khan, Shakeel Ahmad, et al.
Publicado: (2023)

Attenuation of quorum sensing system and virulence in Vibrio cholerae by phytomolecules
por: Saha, Subhasree, et al.
Publicado: (2023)

Discovering Potential Anti-Oral Squamous Cell Carcinoma Mechanisms from Kochiae Fructus Using Network-Based Pharmacology Analysis and Experimental Validation
por: Kim, Youn-Sook, et al.
Publicado: (2023)

Understanding the molecular mechanism of Ginkgo Folium-Forsythiae Fructus for cerebral atherosclerosis treatment using network pharmacology and molecular docking
por: Zhang, Jinfei, et al.
Publicado: (2023)

Study on the Potential Mechanism of Fructus Tribuli in the Treatment of Hypertensive Vascular Remodeling Based on Network Pharmacology and Molecular Docking
por: Wang, Shuyue, et al.
Publicado: (2021)

Quantification Analysis and In Vitro Anti-Inflammatory Effects of 20-Hydroxyecdysone, Momordin Ic, and Oleanolic Acid from the Fructus of Kochia scoparia
por: Yoo, Sae-Rom, et al.
Publicado: (2017)

Phytomolecules-Coated NiO Nanoparticles Synthesis Using Abutilon indicum Leaf Extract: Antioxidant, Antibacterial, and Anticancer Activities
por: Khan, Shakeel Ahmad, et al.
Publicado: (2021)

The possible mechanism of Hippophae fructus oil applied in tympanic membrane repair identified based on network pharmacology and molecular docking
por: Huang, Juntao, et al.
Publicado: (2021)

Exploring Anti-Nonalcoholic Fatty Liver Disease Mechanism of Gardeniae Fructus by Network Pharmacology, Molecular Docking, and Experiment Validation
por: Tang, Zhongyan, et al.
Publicado: (2022)

Hepatotoxic Components Effect of Chebulae Fructus and Associated Molecular Mechanism by Integrated Transcriptome and Molecular Docking
por: Ai, Liwen, et al.
Publicado: (2023)

Assessing the Mechanism of Action of “Fructus Ligustri Lucidi-Cuscutae Semen” in Prostate Cancer Treatment Using Network Pharmacology and Molecular Docking
por: Lu, Dongdong, et al.
Publicado: (2022)

Fitness Outcomes Related to Glyphosate Resistance in Kochia (Kochia scoparia): What Life History Stage to Examine?
por: Osipitan, Omobolanle Adewale, et al.
Publicado: (2017)

Molecular mechanisms of Huanglian Jiedu decoction in treating Alzheimer’s disease by regulating microbiome via network pharmacology and molecular docking analysis
por: Zheng, Renyuan, et al.
Publicado: (2023)

Phytomolecules Repurposed as Covid-19 Inhibitors: Opportunity and Challenges
por: Chandramouli, Vaishnavi, et al.
Publicado: (2021)

Pharmacologically Active Phytomolecules Isolated from Traditional Antidiabetic Plants and Their Therapeutic Role for the Management of Diabetes Mellitus
por: Ansari, Prawej, et al.
Publicado: (2022)

A bioinformatics investigation into molecular mechanism of Yinzhihuang granules for treating hepatitis B by network pharmacology and molecular docking verification
por: Zhang, Jingyuan, et al.
Publicado: (2020)

An Integrated Analysis of Network Pharmacology, Molecular Docking, and Experiment Validation to Explore the New Candidate Active Component and Mechanism of Cuscutae Semen-Mori Fructus Coupled-Herbs in Treating Oligoasthenozoospermia
por: Bai, Xue, et al.
Publicado: (2021)

Investigation on the mechanisms of guiqi huoxue capsule for treating cervical spondylosis based on network pharmacology and molecular docking
por: Liu, Yingying, et al.
Publicado: (2021)

Network Pharmacology and Molecular Docking Elucidate the Pharmacological Mechanism of the OSTEOWONDER Capsule for Treating Osteoporosis
por: Fan, Jiashuang, et al.
Publicado: (2022)

Based on UPLC-Q-TOF-MS/MS, Systematic Network Pharmacology, and Molecular Docking to Explore the Potential Mechanism of Fructus Aurantii for Major Depression Disorder
por: Xie, Yating, et al.
Publicado: (2021)

Mechanism of N-0385 blocking SARS-CoV-2 to treat COVID-19 based on molecular docking and molecular dynamics
por: Cao, Jun-Feng, et al.
Publicado: (2022)

Investigation of the hemostatic mechanism of Gardeniae fructus Praeparatus based on pharmacological evaluation and network pharmacology
por: Zheng, Yinghao, et al.
Publicado: (2022)

The Anti-Inflammatory Effect of Fructus Kochiae on Allergic Contact Dermatitis Rats via pERK1/2/TLR4/NF-κB Pathway Activation
por: Xiao, Zuoqi, et al.
Publicado: (2018)

Investigating the molecular mechanism of iguratimod act on SLE using network pharmacology and molecular docking analysis
por: Zeng, Huiqiong, et al.
Publicado: (2022)

Molecular targets and mechanisms of Guanxinning tablet in treating atherosclerosis: Network pharmacology and molecular docking analysis
por: Niu, Chaofeng, et al.
Publicado: (2023)

The potential mechanism of Fructus Ligustri Lucidi promoting osteogenetic differentiation of bone marrow mesenchymal stem cells based on network pharmacology, molecular docking and experimental identification
por: Kong, Yuanhang, et al.
Publicado: (2022)

Investigation on the Mechanisms of Zanthoxylum bungeanum for Treating Diabetes Mellitus Based on Network Pharmacology, Molecular Docking, and Experiment Verification
por: Huang, Yuanshe, et al.
Publicado: (2023)

Network Pharmacology and Molecular Docking Analysis on the Pharmacological Mechanisms of Modified Sanmiaosan in Treating Ulcerative Colitis
por: Wang, Yong, et al.
Publicado: (2022)

Unraveling the Molecular Mechanisms of Fructus Anisi Stellati as a Remedy for Infantile Colic by Network Pharmacology
por: Li, Xingyu, et al.
Publicado: (2020)

Icaritin, an Exogenous Phytomolecule, Enhances Osteogenesis but Not Angiogenesis—An In Vitro Efficacy Study
por: Yao, Dong, et al.
Publicado: (2012)

Network Pharmacology, Molecular Docking, and Molecular Dynamic-Based Investigation on the Mechanism of Compound Chrysanthemum in the Treatment of Asthenopia
por: Qiu, Junjie, et al.
Publicado: (2022)

Investigating the presence of compensatory evolution in dicamba resistant IAA16 mutated kochia (Bassia scoparia)(†)
por: Wu, Chenxi, et al.
Publicado: (2020)

Research on the Mechanism of Kaempferol for Treating Senile Osteoporosis by Network Pharmacology and Molecular Docking
por: Tang, Fuyu, et al.
Publicado: (2022)

Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking
por: Ou, Chen, et al.
Publicado: (2020)

Discussion on the molecular mechanism of Duhuo Jisheng decoction in treating osteoarthritis based on network pharmacology and molecular docking
por: Yang, Liu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_auiv2qknl4omunvsi2demf20a1