Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST(2) and SST(5) homo- and hetero-dimer formation

The process of GPCR dimerization can have profound effects on GPCR activation, signaling, and intracellular trafficking. Somatostatin receptors (SSTs) are class A GPCRs abundantly expressed in pituitary tumors where they represent the main pharmacological targets of somatostatin analogs (SSAs), than...

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Detalles Bibliográficos
Autores principales: Treppiedi, Donatella, Marra, Giusy, Di Muro, Genesio, Catalano, Rosa, Mangili, Federica, Esposito, Emanuela, Calebiro, Davide, Arosio, Maura, Peverelli, Erika, Mantovani, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389162/
https://www.ncbi.nlm.nih.gov/pubmed/35992099
http://dx.doi.org/10.3389/fendo.2022.892668

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