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Exendin-4 alleviates β-Amyloid peptide toxicity via DAF-16 in a Caenorhabditis elegans model of Alzheimer's disease

Epidemiological analyses indicate that type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimer's disease (AD). They share common pathophysiological mechanisms. Thus, it has been increasingly suggested that several anti-T2DM drugs may have therapeutic potential in AD. Exendin-4, as a gluc...

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Detalles Bibliográficos
Autores principales: Song, Xiangwei, Sun, Yingqi, Wang, Zhun, Su, Yingying, Wang, Yangkun, Wang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389237/
https://www.ncbi.nlm.nih.gov/pubmed/35992601
http://dx.doi.org/10.3389/fnagi.2022.955113

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