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Ligands can differentially and temporally modulate GPCR interaction with 14-3-3 isoforms

GPCR signaling and function depend on their associated proteins and subcellular locations. Besides G-proteins and β-arrestins, 14-3-3 proteins participate in GPCR trafficking and signaling, and they connect a large number of diverse proteins to form signaling networks. Multiple 14-3-3 isoforms exist...

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Detalles Bibliográficos
Autores principales:	Eishingdrelo, Haifeng, Qin, Xiaofa, Yuan, Luwa, Kongsamut, Sathapana, Yu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	COVID-19 therapy edited by Isabella Zanella & Simon Pitchford
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389249/ https://www.ncbi.nlm.nih.gov/pubmed/35992381 http://dx.doi.org/10.1016/j.crphar.2022.100123

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