EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression

Triple-negative breast cancers (TNBCs) are frequently poorly differentiated with high propensity for metastasis. Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 that mediates transcriptional repression in normal cells and in cancer through H3K27me3...

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Detalles Bibliográficos
Autores principales: Gonzalez, Maria E., Naimo, Giuseppina Daniela, Anwar, Talha, Paolì, Alessandro, Tekula, Shilpa R., Kim, Suny, Medhora, Natasha, Leflein, Shoshana A., Itkin, Jacob, Trievel, Raymond, Kidwell, Kelley M., Chen, Yu-Chih, Mauro, Loredana, Yoon, Euisik, Andò, Sebastiano, Kleer, Celina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389258/
https://www.ncbi.nlm.nih.gov/pubmed/35992062
http://dx.doi.org/10.1016/j.isci.2022.104827

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