Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutatnt colorectal cancer

Ferroptosis, a new form of regulated cell death triggered by the iron-dependent peroxidation of phospholipids, is associated with cellular metabolism, redox homeostasis, and various signaling pathways related to cancer. Aspirin is a widely used non-steroidal anti-inflammatory drug (NSAID) and has be...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Qi, Qinqin, Wu, Nan, Wang, Ying, Feng, Qian, Jin, Rong, Jiang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389304/
https://www.ncbi.nlm.nih.gov/pubmed/35963119
http://dx.doi.org/10.1016/j.redox.2022.102426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389304/
https://www.ncbi.nlm.nih.gov/pubmed/35963119
http://dx.doi.org/10.1016/j.redox.2022.102426

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