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Protocol for stratification of triple-negative breast cancer patients using in silico signaling dynamics
Personalized kinetic models can predict potential biomarkers and drug targets. Here, we provide a step-by-step approach for building an executable mathematical model from text and integrating transcriptomic datasets. We additionally describe the steps to personalize the mechanistic model and to stra...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389415/ https://www.ncbi.nlm.nih.gov/pubmed/35990741 http://dx.doi.org/10.1016/j.xpro.2022.101619 |