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Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes

[Image: see text] Recombinantly produced biotherapeutics hold promise for improving the current standard of care for snakebite envenoming over conventional serotherapy. Nanobodies have performed well in the clinic, and in the context of antivenom, they have shown the ability to neutralize long α-neu...

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Detalles Bibliográficos
Autores principales:	Wade, Jack, Rimbault, Charlotte, Ali, Hanif, Ledsgaard, Line, Rivera-de-Torre, Esperanza, Abou Hachem, Maher, Boddum, Kim, Mirza, Nadia, Bohn, Markus-Frederik, Sakya, Siri A., Ruso-Julve, Fulgencio, Andersen, Jan Terje, Laustsen, Andreas H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389527/ https://www.ncbi.nlm.nih.gov/pubmed/35875886 http://dx.doi.org/10.1021/acs.bioconjchem.2c00220

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