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Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up
BACKGROUND AND AIM: A technique of endoscopic tightening of the cardia mucosa for the treatment of gastroesophageal reflux disease (GERD) was developed and its clinical efficacy was observed. METHODS: 120 patients with GERD who underwent endoscopic tightening surgery from December 2017 to December 2...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Whioce Publishing Pte. Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389572/ https://www.ncbi.nlm.nih.gov/pubmed/35475271 |
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author | Li, Zhenhua Li, Yongliang Wu, Yue Li, Mingyan Yan, Zhaobin Nie, Shanwen Liang, Zhitao Li, Bo Zhu, Peiwen Cui, Peilin Zhang, Qinsheng |
author_facet | Li, Zhenhua Li, Yongliang Wu, Yue Li, Mingyan Yan, Zhaobin Nie, Shanwen Liang, Zhitao Li, Bo Zhu, Peiwen Cui, Peilin Zhang, Qinsheng |
author_sort | Li, Zhenhua |
collection | PubMed |
description | BACKGROUND AND AIM: A technique of endoscopic tightening of the cardia mucosa for the treatment of gastroesophageal reflux disease (GERD) was developed and its clinical efficacy was observed. METHODS: 120 patients with GERD who underwent endoscopic tightening surgery from December 2017 to December 2019 were included in this study. GERD-Q score and constitution type of patients were evaluated preoperatively and at 1 month, 3 months, 6 months, and 1 year after surgery. In addition, effectiveness and side effects of the procedure were graded based on gastroesophageal flap valve (GEFV) function. RESULTS: GERD-Q score of 1 month, 3 months, 6 months, and 1 year after surgery were significantly decreased (P<0.01) compared with preoperative score. There were no significant differences between GERD-Q score of 1 month, 3 months, 6 months, and 1 year after surgery. The surgery proves to be effective in all GEFV grades, especially in Hill-III. CONCLUSION: Endoscopic tightening is an effective method for the treatment of patients with GERD, especially of Hill-III patients. Attention should be paid to cardia width, ligation ring depth, and ring number during operation. RELEVANCE FOR PATIENTS: ETCM is a safe endoscopic procedure with minimal trauma, which has been proved effective for patients who are diagnosed with GERD. |
format | Online Article Text |
id | pubmed-9389572 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Whioce Publishing Pte. Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93895722022-08-19 Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up Li, Zhenhua Li, Yongliang Wu, Yue Li, Mingyan Yan, Zhaobin Nie, Shanwen Liang, Zhitao Li, Bo Zhu, Peiwen Cui, Peilin Zhang, Qinsheng J Clin Transl Res Original Article BACKGROUND AND AIM: A technique of endoscopic tightening of the cardia mucosa for the treatment of gastroesophageal reflux disease (GERD) was developed and its clinical efficacy was observed. METHODS: 120 patients with GERD who underwent endoscopic tightening surgery from December 2017 to December 2019 were included in this study. GERD-Q score and constitution type of patients were evaluated preoperatively and at 1 month, 3 months, 6 months, and 1 year after surgery. In addition, effectiveness and side effects of the procedure were graded based on gastroesophageal flap valve (GEFV) function. RESULTS: GERD-Q score of 1 month, 3 months, 6 months, and 1 year after surgery were significantly decreased (P<0.01) compared with preoperative score. There were no significant differences between GERD-Q score of 1 month, 3 months, 6 months, and 1 year after surgery. The surgery proves to be effective in all GEFV grades, especially in Hill-III. CONCLUSION: Endoscopic tightening is an effective method for the treatment of patients with GERD, especially of Hill-III patients. Attention should be paid to cardia width, ligation ring depth, and ring number during operation. RELEVANCE FOR PATIENTS: ETCM is a safe endoscopic procedure with minimal trauma, which has been proved effective for patients who are diagnosed with GERD. Whioce Publishing Pte. Ltd. 2022-03-01 /pmc/articles/PMC9389572/ /pubmed/35475271 Text en Copyright: © 2022 Author(s). https://creativecommons.org/licenses/by-nc/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution-Noncommercial License, permitting all noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Li, Zhenhua Li, Yongliang Wu, Yue Li, Mingyan Yan, Zhaobin Nie, Shanwen Liang, Zhitao Li, Bo Zhu, Peiwen Cui, Peilin Zhang, Qinsheng Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title | Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title_full | Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title_fullStr | Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title_full_unstemmed | Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title_short | Endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: A case series of 120 patients up to 1-year follow-up |
title_sort | endoscopic tightening of the cardia mucosa in gastroesophageal reflux disease: a case series of 120 patients up to 1-year follow-up |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389572/ https://www.ncbi.nlm.nih.gov/pubmed/35475271 |
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