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Mutually Exclusive Interactions of Rifabutin with Spatially Distinct Mycobacterial Cell Envelope Membrane Layers Offer Insights into Membrane-Centric Therapy of Infectious Diseases

[Image: see text] The mycobacterial cell envelope has spatially resolved inner and outer membrane layers with distinct compositions and membrane properties. However, the functional implication and relevance of this organization remain unknown. Using membrane biophysics and molecular simulations, we...

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Detalles Bibliográficos
Autores principales:	Menon, Anjana P., Dong, Wanqian, Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Duan, Mojie, Kapoor, Shobhna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389580/ https://www.ncbi.nlm.nih.gov/pubmed/35996474 http://dx.doi.org/10.1021/acsbiomedchemau.2c00010

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