Elucidating the Oligomerization and Cellular Interactions of a Trimer Derived from Aβ through Fluorescence and Mass Spectrometric Studies

[Image: see text] Aβ oligomers play a central role in the neurodegeneration observed with Alzheimer’s disease. Our laboratory has developed covalently stabilized trimers derived from residues 17–36 of Aβ as model systems for studying Aβ oligomers. In the current study, we apply the emerging techniqu...

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Detalles Bibliográficos
Autores principales: Guaglianone, Gretchen, Torrado, Belén, Lin, Yu-Fu, Watkins, Matthew C., Wysocki, Vicki H., Gratton, Enrico, Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389591/
https://www.ncbi.nlm.nih.gov/pubmed/35892278
http://dx.doi.org/10.1021/acschemneuro.2c00313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389591/
https://www.ncbi.nlm.nih.gov/pubmed/35892278
http://dx.doi.org/10.1021/acschemneuro.2c00313

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