A machine learning model for classifying G-protein-coupled receptors as agonists or antagonists

BACKGROUND: G-protein coupled receptors (GPCRs) sense and transmit extracellular signals into the intracellular machinery by regulating G proteins. GPCR malfunctions are associated with a variety of signaling-related diseases, including cancer and diabetes; at least a third of the marketed drugs tar...

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Detalles Bibliográficos
Autores principales: Oh, Jooseong, Ceong, Hyi-thaek, Na, Dokyun, Park, Chungoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389651/
https://www.ncbi.nlm.nih.gov/pubmed/35982407
http://dx.doi.org/10.1186/s12859-022-04877-7

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