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Melatonin inhibits NaIO(3)-induced ARPE-19 cell apoptosis via suppression of HIF-1α/BNIP3-LC3B/mitophagy signaling

BACKGROUND: Age-related macular degeneration (AMD) leads to gradual central vision loss and eventual irreversible blindness. Melatonin, an endogenous hormone, exhibits anti-inflammatory and antitumor effects; however, the role it plays in AMD remains unclear. Herein, we investigated the anti-AMD mol...

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Detalles Bibliográficos
Autores principales:	Wang, Kai, Chen, Yong-Syuan, Chien, Hsiang-Wen, Chiou, Hui-Ling, Yang, Shun-Fa, Hsieh, Yi-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389659/ https://www.ncbi.nlm.nih.gov/pubmed/35986432 http://dx.doi.org/10.1186/s13578-022-00879-3

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