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Vitamin D status and its correlation to depression

BACKGROUND: Vitamin D can influence more than 200 genes in various tissues showing its credibility among the fat-soluble vitamins. Vitamin D deficiency is directly proportional to major clinical conditions such as cardiovascular diseases, diabetes, malignancy, and multiple sclerosis. This study was...

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Autores principales: khan, Bashir, Shafiq, Huma, Abbas, Seyyedha, Jabeen, Summeira, Khan, Sikandar Ali, Afsar, Tayyaba, Almajwal, Ali, Alruwaili, Nawaf W., al-disi, Dara, Alenezi, Sultan, Parveen, Zahida, Razak, Suhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389668/
https://www.ncbi.nlm.nih.gov/pubmed/35982462
http://dx.doi.org/10.1186/s12991-022-00406-1
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author khan, Bashir
Shafiq, Huma
Abbas, Seyyedha
Jabeen, Summeira
Khan, Sikandar Ali
Afsar, Tayyaba
Almajwal, Ali
Alruwaili, Nawaf W.
al-disi, Dara
Alenezi, Sultan
Parveen, Zahida
Razak, Suhail
author_facet khan, Bashir
Shafiq, Huma
Abbas, Seyyedha
Jabeen, Summeira
Khan, Sikandar Ali
Afsar, Tayyaba
Almajwal, Ali
Alruwaili, Nawaf W.
al-disi, Dara
Alenezi, Sultan
Parveen, Zahida
Razak, Suhail
author_sort khan, Bashir
collection PubMed
description BACKGROUND: Vitamin D can influence more than 200 genes in various tissues showing its credibility among the fat-soluble vitamins. Vitamin D deficiency is directly proportional to major clinical conditions such as cardiovascular diseases, diabetes, malignancy, and multiple sclerosis. This study was conducted to determine the vitamin D level of individuals and its association with depression. METHODS: Vitamin D levels of 100 healthy and 100 depressed subjects were determined. The isolated subjects were screened on the Beck Depression Inventory (BDI) scale and divided into three groups according to their age. Group-I comprised subjects of age 20 years and below, Group-II included subjects of age 21 to 60, and Group-III comprised subjects of ≥ 61 years of age. A sufficient level of vitamin D in normal subjects was noted, while mild deficiency of vitamin D status was observed in depressed subjects. RESULTS: Our study has reported a higher percentage of vitamin D deficiency in the Peshawar region. The results of our study indicated that depression was common in individuals having vitamin D deficiency. CONCLUSIONS: The study showed a very high frequency of vitamin D deficiency in subjects with depression in Peshawar, Pakistan. The deficiency of vitamin D was observed more in females as compared to males. Further studies should explicate whether the highly widespread vitamin D deficiency could be cost-effectively treated as part of preventive or treatment interventions for depression. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12991-022-00406-1.
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spelling pubmed-93896682022-08-20 Vitamin D status and its correlation to depression khan, Bashir Shafiq, Huma Abbas, Seyyedha Jabeen, Summeira Khan, Sikandar Ali Afsar, Tayyaba Almajwal, Ali Alruwaili, Nawaf W. al-disi, Dara Alenezi, Sultan Parveen, Zahida Razak, Suhail Ann Gen Psychiatry Research BACKGROUND: Vitamin D can influence more than 200 genes in various tissues showing its credibility among the fat-soluble vitamins. Vitamin D deficiency is directly proportional to major clinical conditions such as cardiovascular diseases, diabetes, malignancy, and multiple sclerosis. This study was conducted to determine the vitamin D level of individuals and its association with depression. METHODS: Vitamin D levels of 100 healthy and 100 depressed subjects were determined. The isolated subjects were screened on the Beck Depression Inventory (BDI) scale and divided into three groups according to their age. Group-I comprised subjects of age 20 years and below, Group-II included subjects of age 21 to 60, and Group-III comprised subjects of ≥ 61 years of age. A sufficient level of vitamin D in normal subjects was noted, while mild deficiency of vitamin D status was observed in depressed subjects. RESULTS: Our study has reported a higher percentage of vitamin D deficiency in the Peshawar region. The results of our study indicated that depression was common in individuals having vitamin D deficiency. CONCLUSIONS: The study showed a very high frequency of vitamin D deficiency in subjects with depression in Peshawar, Pakistan. The deficiency of vitamin D was observed more in females as compared to males. Further studies should explicate whether the highly widespread vitamin D deficiency could be cost-effectively treated as part of preventive or treatment interventions for depression. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12991-022-00406-1. BioMed Central 2022-08-18 /pmc/articles/PMC9389668/ /pubmed/35982462 http://dx.doi.org/10.1186/s12991-022-00406-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
khan, Bashir
Shafiq, Huma
Abbas, Seyyedha
Jabeen, Summeira
Khan, Sikandar Ali
Afsar, Tayyaba
Almajwal, Ali
Alruwaili, Nawaf W.
al-disi, Dara
Alenezi, Sultan
Parveen, Zahida
Razak, Suhail
Vitamin D status and its correlation to depression
title Vitamin D status and its correlation to depression
title_full Vitamin D status and its correlation to depression
title_fullStr Vitamin D status and its correlation to depression
title_full_unstemmed Vitamin D status and its correlation to depression
title_short Vitamin D status and its correlation to depression
title_sort vitamin d status and its correlation to depression
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389668/
https://www.ncbi.nlm.nih.gov/pubmed/35982462
http://dx.doi.org/10.1186/s12991-022-00406-1
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