Poly(ADP-ribosyl)ation of acetyltransferase NAT10 by PARP1 is required for its nucleoplasmic translocation and function in response to DNA damage

BACKGROUND: N-acetyltransferase 10 (NAT10), an abundant nucleolar protein with both lysine and RNA cytidine acetyltransferase activities, has been implicated in Hutchinson-Gilford progeria syndrome and human cancer. We and others recently demonstrated that NAT10 is translocated from the nucleolus to...

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Detalles Bibliográficos
Autores principales: Liu, Hong-Yi, Liu, Ying-Ying, Zhang, Yin-Ling, Ning, Yan, Zhang, Fang-Lin, Li, Da-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389688/
https://www.ncbi.nlm.nih.gov/pubmed/35986334
http://dx.doi.org/10.1186/s12964-022-00932-1

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