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Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics
BACKGROUND: Glioblastoma (GBM) represents nearly one-half of primary brain tumors, and the median survival of patients with GBM is only 14.6 months. Surgery followed by radiation with concomitant temozolomide (TMZ) therapy is currently the standard of care. However, an increasing body of evidence su...
Autores principales: | Chen, Hao, Li, Chunlin, Hu, Haiyang, Zhang, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389719/ https://www.ncbi.nlm.nih.gov/pubmed/35982414 http://dx.doi.org/10.1186/s12860-022-00438-1 |
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