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Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM

BACKGROUND: The suggested effects of the oocyte secreted GDF9 and BMP15 growth factors on oocyte maturation are currently based on recombinant proteins, and little is known about native GDF9 and BMP15 in humans. METHODS: Human immature cumulus-oocyte complexes (COCs) obtained in connection with ovar...

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Detalles Bibliográficos
Autores principales: Cadenas, Jesús, Pors, Susanne Elisabeth, Kumar, Ajay, Kalra, Bhanu, Kristensen, Stine Gry, Andersen, Claus Yding, Mamsen, Linn Salto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389727/
https://www.ncbi.nlm.nih.gov/pubmed/35986324
http://dx.doi.org/10.1186/s12958-022-01000-6