Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic rats

BACKGROUND: Mesenchymal stem cells (MSCs) exert anti-diabetic effects and improve long-term complications via secretory effects that regulate macrophage polarisation and attenuate inflammation. Enhancing the efficacy of MSCs needs to be explored further. The in vitro culture microenvironment influen...

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Detalles Bibliográficos
Autores principales: Su, Wanlu, Yu, Songyan, Yin, Yaqi, Li, Bing, Xue, Jing, Wang, Jie, Gu, Yulin, Zhang, Haixia, Lyu, Zhaohui, Mu, Yiming, Cheng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389728/
https://www.ncbi.nlm.nih.gov/pubmed/35986406
http://dx.doi.org/10.1186/s13287-022-03114-5

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