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Circular RNA circFIRRE drives osteosarcoma progression and metastasis through tumorigenic-angiogenic coupling

BACKGROUND: Disappointing clinical efficacy of standard treatment has been proven in refractory metastatic osteosarcoma, and the emerging anti-angiogenic regimens are still in the infantile stage. Thus, there is an urgent need to develop novel therapeutic approach for osteosarcoma lung metastasis. M...

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Detalles Bibliográficos
Autores principales: Yu, Lingfeng, Zhu, Hao, Wang, Zhen, Huang, Jianhao, Zhu, Yan, Fan, Gentao, Wang, Yicun, Chen, Xi, Zhou, Guangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389772/
https://www.ncbi.nlm.nih.gov/pubmed/35986280
http://dx.doi.org/10.1186/s12943-022-01624-7

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