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Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous and aggressive blood cancer that results from diverse genetic aberrations in the hematopoietic stem or progenitor cells (HSPCs) leading to the expansion of blasts in the hematopoietic system. The heterogeneity and evolution of cancer blasts...

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Detalles Bibliográficos
Autores principales:	Zhai, Yanan, Singh, Prashant, Dolnik, Anna, Brazda, Peter, Atlasy, Nader, del Gaudio, Nunzio, Döhner, Konstanze, Döhner, Hartmut, Minucci, Saverio, Martens, Joost, Altucci, Lucia, Megchelenbrink, Wout, Bullinger, Lars, Stunnenberg, Hendrik G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389773/ https://www.ncbi.nlm.nih.gov/pubmed/35986270 http://dx.doi.org/10.1186/s12943-022-01635-4

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