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3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor

BACKGROUND: Several new generation CDK4/6 inhibitors have been developed and approved for breast cancer therapy in combination with endocrine therapeutics. Application of these inhibitors either alone or in combination in other solid tumors has been proposed, but no imaging biomarkers of response ha...

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Detalles Bibliográficos
Autores principales:	Tatum, James L., Kalen, Joseph D., Jacobs, Paula M., Riffle, Lisa A., James, Amy, Thang, Lai, Sanders, Chelsea, Hollingshead, Melinda G., Basuli, Falguni, Shi, Jianfeng, Doroshow, James H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389794/ https://www.ncbi.nlm.nih.gov/pubmed/35982453 http://dx.doi.org/10.1186/s12967-022-03580-8

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