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Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

BACKGROUND: Polycystic ovary syndrome (PCOS), characterized by androgen excess and ovulatory dysfunction, is associated with a high prevalence of obesity and insulin resistance (IR) in women. We demonstrated that sodium–glucose cotransporter-2 inhibitor (SGLT2i) administration decreases fat mass wit...

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Detalles Bibliográficos
Autores principales: Pruett, Jacob E., Everman, Steven J., Hoang, Ngoc H., Salau, Faridah, Taylor, Lucy C., Edwards, Kristin S., Hosler, Jonathan P., Huffman, Alexandra M., Romero, Damian G., Yanes Cardozo, Licy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389812/
https://www.ncbi.nlm.nih.gov/pubmed/35986388
http://dx.doi.org/10.1186/s13293-022-00455-x

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