The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022

A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body,...

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Autores principales: Veintimilla, Cristina, Catalán, Pilar, Alonso, Roberto, de Viedma, Darío García, Pérez-Lago, Laura, Palomo, María, Cobos, Alejandro, Aldamiz-Echevarria, Teresa, Muñoz, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389859/
https://www.ncbi.nlm.nih.gov/pubmed/35983771
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.33.2200598
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author Veintimilla, Cristina
Catalán, Pilar
Alonso, Roberto
de Viedma, Darío García
Pérez-Lago, Laura
Palomo, María
Cobos, Alejandro
Aldamiz-Echevarria, Teresa
Muñoz, Patricia
author_facet Veintimilla, Cristina
Catalán, Pilar
Alonso, Roberto
de Viedma, Darío García
Pérez-Lago, Laura
Palomo, María
Cobos, Alejandro
Aldamiz-Echevarria, Teresa
Muñoz, Patricia
author_sort Veintimilla, Cristina
collection PubMed
description A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body, followed by plasma, pharyngeal and anal swabs. Testing specimens from multiple sites may improve the sensitivity and reduce false-negative test results.
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spelling pubmed-93898592022-09-13 The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022 Veintimilla, Cristina Catalán, Pilar Alonso, Roberto de Viedma, Darío García Pérez-Lago, Laura Palomo, María Cobos, Alejandro Aldamiz-Echevarria, Teresa Muñoz, Patricia Euro Surveill Rapid Communication A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body, followed by plasma, pharyngeal and anal swabs. Testing specimens from multiple sites may improve the sensitivity and reduce false-negative test results. European Centre for Disease Prevention and Control (ECDC) 2022-08-18 /pmc/articles/PMC9389859/ /pubmed/35983771 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.33.2200598 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Veintimilla, Cristina
Catalán, Pilar
Alonso, Roberto
de Viedma, Darío García
Pérez-Lago, Laura
Palomo, María
Cobos, Alejandro
Aldamiz-Echevarria, Teresa
Muñoz, Patricia
The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title_full The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title_fullStr The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title_full_unstemmed The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title_short The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
title_sort relevance of multiple clinical specimens in the diagnosis of monkeypox virus, spain, june 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389859/
https://www.ncbi.nlm.nih.gov/pubmed/35983771
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.33.2200598
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