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Coronary artery bypass grafts to chronic occluded right coronary arteries
BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associate...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390466/ https://www.ncbi.nlm.nih.gov/pubmed/36003729 http://dx.doi.org/10.1016/j.xjon.2021.06.007 |
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author | Fiddicke, Maleen Fleissner, Felix Brunkhorst, Tonita Kühn, Eva M. Obed, Doha Boethig, Dietmar Ismail, Issam Haverich, Axel Warnecke, Gregor Sommer, Wiebke |
author_facet | Fiddicke, Maleen Fleissner, Felix Brunkhorst, Tonita Kühn, Eva M. Obed, Doha Boethig, Dietmar Ismail, Issam Haverich, Axel Warnecke, Gregor Sommer, Wiebke |
author_sort | Fiddicke, Maleen |
collection | PubMed |
description | BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associated with angina. We investigated outcome of patients with total chronic occlusion of the right coronary artery (RCA) receiving coronary artery bypass grafting (CABG) surgery with and without revascularization of the RCA. METHODS: We retrospectively analyzed all patients with chronically occluded RCAs receiving CABG with (group 1 = RCA-CABG; n = 487) and without (group 2 = No-RCA-CABG; n = 100) revascularization of the RCA. In total, 587 patients with complete follow-up of a minimum of 6 years were included (92%). RESULTS: In total, 82% in group 1 versus 86% in group 2 were male (P = .38). European System for Cardiac Operative Risk Evaluation II was comparable between both groups (4.35 ± 7.09% vs 4.80 ± 5.77%, P = .56) with no major differences regarding preoperative characteristics between groups. Patients in group 1 received 3.24 ± 0.79 distal anastomoses, whereas group 2 received 2.45 ± 0.83 distal anastomoses (P < .001). Although in-hospital mortality was comparable (2.9% in group 1 vs 5.0% in group 2, P = .27), long-term survival was significantly better in group 1 (P = .002). No difference in the incidence of further major adverse cardiac and cerebrovascular events was found. CONCLUSIONS: Patients with a chronically occluded RCA undergoing CABG who did not receive an RCA graft showed a significantly reduced long-term survival. Given the herein presented data, revascularization of chronically occluded right arteries during CABG should be recommended whenever technically feasible. |
format | Online Article Text |
id | pubmed-9390466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-93904662022-08-23 Coronary artery bypass grafts to chronic occluded right coronary arteries Fiddicke, Maleen Fleissner, Felix Brunkhorst, Tonita Kühn, Eva M. Obed, Doha Boethig, Dietmar Ismail, Issam Haverich, Axel Warnecke, Gregor Sommer, Wiebke JTCVS Open Adult: Coronary BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associated with angina. We investigated outcome of patients with total chronic occlusion of the right coronary artery (RCA) receiving coronary artery bypass grafting (CABG) surgery with and without revascularization of the RCA. METHODS: We retrospectively analyzed all patients with chronically occluded RCAs receiving CABG with (group 1 = RCA-CABG; n = 487) and without (group 2 = No-RCA-CABG; n = 100) revascularization of the RCA. In total, 587 patients with complete follow-up of a minimum of 6 years were included (92%). RESULTS: In total, 82% in group 1 versus 86% in group 2 were male (P = .38). European System for Cardiac Operative Risk Evaluation II was comparable between both groups (4.35 ± 7.09% vs 4.80 ± 5.77%, P = .56) with no major differences regarding preoperative characteristics between groups. Patients in group 1 received 3.24 ± 0.79 distal anastomoses, whereas group 2 received 2.45 ± 0.83 distal anastomoses (P < .001). Although in-hospital mortality was comparable (2.9% in group 1 vs 5.0% in group 2, P = .27), long-term survival was significantly better in group 1 (P = .002). No difference in the incidence of further major adverse cardiac and cerebrovascular events was found. CONCLUSIONS: Patients with a chronically occluded RCA undergoing CABG who did not receive an RCA graft showed a significantly reduced long-term survival. Given the herein presented data, revascularization of chronically occluded right arteries during CABG should be recommended whenever technically feasible. Elsevier 2021-06-09 /pmc/articles/PMC9390466/ /pubmed/36003729 http://dx.doi.org/10.1016/j.xjon.2021.06.007 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Adult: Coronary Fiddicke, Maleen Fleissner, Felix Brunkhorst, Tonita Kühn, Eva M. Obed, Doha Boethig, Dietmar Ismail, Issam Haverich, Axel Warnecke, Gregor Sommer, Wiebke Coronary artery bypass grafts to chronic occluded right coronary arteries |
title | Coronary artery bypass grafts to chronic occluded right coronary arteries |
title_full | Coronary artery bypass grafts to chronic occluded right coronary arteries |
title_fullStr | Coronary artery bypass grafts to chronic occluded right coronary arteries |
title_full_unstemmed | Coronary artery bypass grafts to chronic occluded right coronary arteries |
title_short | Coronary artery bypass grafts to chronic occluded right coronary arteries |
title_sort | coronary artery bypass grafts to chronic occluded right coronary arteries |
topic | Adult: Coronary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390466/ https://www.ncbi.nlm.nih.gov/pubmed/36003729 http://dx.doi.org/10.1016/j.xjon.2021.06.007 |
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