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Coronary artery bypass grafts to chronic occluded right coronary arteries

BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associate...

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Autores principales: Fiddicke, Maleen, Fleissner, Felix, Brunkhorst, Tonita, Kühn, Eva M., Obed, Doha, Boethig, Dietmar, Ismail, Issam, Haverich, Axel, Warnecke, Gregor, Sommer, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390466/
https://www.ncbi.nlm.nih.gov/pubmed/36003729
http://dx.doi.org/10.1016/j.xjon.2021.06.007
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author Fiddicke, Maleen
Fleissner, Felix
Brunkhorst, Tonita
Kühn, Eva M.
Obed, Doha
Boethig, Dietmar
Ismail, Issam
Haverich, Axel
Warnecke, Gregor
Sommer, Wiebke
author_facet Fiddicke, Maleen
Fleissner, Felix
Brunkhorst, Tonita
Kühn, Eva M.
Obed, Doha
Boethig, Dietmar
Ismail, Issam
Haverich, Axel
Warnecke, Gregor
Sommer, Wiebke
author_sort Fiddicke, Maleen
collection PubMed
description BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associated with angina. We investigated outcome of patients with total chronic occlusion of the right coronary artery (RCA) receiving coronary artery bypass grafting (CABG) surgery with and without revascularization of the RCA. METHODS: We retrospectively analyzed all patients with chronically occluded RCAs receiving CABG with (group 1 = RCA-CABG; n = 487) and without (group 2 = No-RCA-CABG; n = 100) revascularization of the RCA. In total, 587 patients with complete follow-up of a minimum of 6 years were included (92%). RESULTS: In total, 82% in group 1 versus 86% in group 2 were male (P = .38). European System for Cardiac Operative Risk Evaluation II was comparable between both groups (4.35 ± 7.09% vs 4.80 ± 5.77%, P = .56) with no major differences regarding preoperative characteristics between groups. Patients in group 1 received 3.24 ± 0.79 distal anastomoses, whereas group 2 received 2.45 ± 0.83 distal anastomoses (P < .001). Although in-hospital mortality was comparable (2.9% in group 1 vs 5.0% in group 2, P = .27), long-term survival was significantly better in group 1 (P = .002). No difference in the incidence of further major adverse cardiac and cerebrovascular events was found. CONCLUSIONS: Patients with a chronically occluded RCA undergoing CABG who did not receive an RCA graft showed a significantly reduced long-term survival. Given the herein presented data, revascularization of chronically occluded right arteries during CABG should be recommended whenever technically feasible.
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spelling pubmed-93904662022-08-23 Coronary artery bypass grafts to chronic occluded right coronary arteries Fiddicke, Maleen Fleissner, Felix Brunkhorst, Tonita Kühn, Eva M. Obed, Doha Boethig, Dietmar Ismail, Issam Haverich, Axel Warnecke, Gregor Sommer, Wiebke JTCVS Open Adult: Coronary BACKGROUND: The benefit of revascularizing chronically occluded coronary arteries remains debatable, and available long-term outcome reports are sparse. Current guidelines recommend revascularization of chronically occluded arteries only in patients with myocardial ischemia and/or symptoms associated with angina. We investigated outcome of patients with total chronic occlusion of the right coronary artery (RCA) receiving coronary artery bypass grafting (CABG) surgery with and without revascularization of the RCA. METHODS: We retrospectively analyzed all patients with chronically occluded RCAs receiving CABG with (group 1 = RCA-CABG; n = 487) and without (group 2 = No-RCA-CABG; n = 100) revascularization of the RCA. In total, 587 patients with complete follow-up of a minimum of 6 years were included (92%). RESULTS: In total, 82% in group 1 versus 86% in group 2 were male (P = .38). European System for Cardiac Operative Risk Evaluation II was comparable between both groups (4.35 ± 7.09% vs 4.80 ± 5.77%, P = .56) with no major differences regarding preoperative characteristics between groups. Patients in group 1 received 3.24 ± 0.79 distal anastomoses, whereas group 2 received 2.45 ± 0.83 distal anastomoses (P < .001). Although in-hospital mortality was comparable (2.9% in group 1 vs 5.0% in group 2, P = .27), long-term survival was significantly better in group 1 (P = .002). No difference in the incidence of further major adverse cardiac and cerebrovascular events was found. CONCLUSIONS: Patients with a chronically occluded RCA undergoing CABG who did not receive an RCA graft showed a significantly reduced long-term survival. Given the herein presented data, revascularization of chronically occluded right arteries during CABG should be recommended whenever technically feasible. Elsevier 2021-06-09 /pmc/articles/PMC9390466/ /pubmed/36003729 http://dx.doi.org/10.1016/j.xjon.2021.06.007 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Adult: Coronary
Fiddicke, Maleen
Fleissner, Felix
Brunkhorst, Tonita
Kühn, Eva M.
Obed, Doha
Boethig, Dietmar
Ismail, Issam
Haverich, Axel
Warnecke, Gregor
Sommer, Wiebke
Coronary artery bypass grafts to chronic occluded right coronary arteries
title Coronary artery bypass grafts to chronic occluded right coronary arteries
title_full Coronary artery bypass grafts to chronic occluded right coronary arteries
title_fullStr Coronary artery bypass grafts to chronic occluded right coronary arteries
title_full_unstemmed Coronary artery bypass grafts to chronic occluded right coronary arteries
title_short Coronary artery bypass grafts to chronic occluded right coronary arteries
title_sort coronary artery bypass grafts to chronic occluded right coronary arteries
topic Adult: Coronary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390466/
https://www.ncbi.nlm.nih.gov/pubmed/36003729
http://dx.doi.org/10.1016/j.xjon.2021.06.007
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