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Splenectomy modulates the immune response but does not prevent joint inflammation in a mouse model of RA
The spleen is the largest secondary lymphoid organ which is involved in the development of B cells and also in systemic (auto)immune responses. Using the recombinant human G1 domain-induced arthritis (GIA) model in splenectomized and control BALB/c mice, we investigated the role of the spleen in the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390846/ https://www.ncbi.nlm.nih.gov/pubmed/35576510 http://dx.doi.org/10.1093/cei/uxac052 |