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Splenectomy modulates the immune response but does not prevent joint inflammation in a mouse model of RA

The spleen is the largest secondary lymphoid organ which is involved in the development of B cells and also in systemic (auto)immune responses. Using the recombinant human G1 domain-induced arthritis (GIA) model in splenectomized and control BALB/c mice, we investigated the role of the spleen in the...

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Detalles Bibliográficos
Autores principales: Khanfar, Esam, Olasz, Katalin, Gajdócsi, Erzsébet, Jia, Xinkai, Berki, Timea, Balogh, Péter, Boldizsár, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390846/
https://www.ncbi.nlm.nih.gov/pubmed/35576510
http://dx.doi.org/10.1093/cei/uxac052