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Dysregulation of the hippocampal neuronal network by LGI1 auto-antibodies

LGI1 is a neuronal secreted protein highly expressed in the hippocampus. Epileptic seizures and LGI1 hypo-functions have been found in both ADLTE, a genetic epileptogenic syndrome and LGI1 limbic encephalitis (LE), an autoimmune disease. Studies, based mainly on transgenic mouse models, investigated...

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Detalles Bibliográficos
Autores principales:	Fels, Elodie, Mayeur, Marie-Eve, Wayere, Estelle, Vincent, Clémentine, Malleval, Céline, Honnorat, Jérôme, Pascual, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390894/ https://www.ncbi.nlm.nih.gov/pubmed/35984846 http://dx.doi.org/10.1371/journal.pone.0272277

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