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Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine

PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the sim...

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Autores principales: Addo, Daniel Akwei, Kaufmann, Elsie Effah, Tagoe, Samuel Nii, Kyere, Augustine Kwame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390906/
https://www.ncbi.nlm.nih.gov/pubmed/35984784
http://dx.doi.org/10.1371/journal.pone.0271000
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author Addo, Daniel Akwei
Kaufmann, Elsie Effah
Tagoe, Samuel Nii
Kyere, Augustine Kwame
author_facet Addo, Daniel Akwei
Kaufmann, Elsie Effah
Tagoe, Samuel Nii
Kyere, Augustine Kwame
author_sort Addo, Daniel Akwei
collection PubMed
description PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron(®) Equinox Cobalt-60 teletherapy machine. METHODS: We examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm × 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle. RESULTS: The estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was ±1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, α = 0.05, n = 11), gantry angle (p = 0.0018, α = 0.05, n = 24), SSD (p = 0.1802, α = 0.05, n = 11) and wedge angle (p = 0.6834, α = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0º), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose. CONCLUSIONS: GafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film.
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spelling pubmed-93909062022-08-20 Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine Addo, Daniel Akwei Kaufmann, Elsie Effah Tagoe, Samuel Nii Kyere, Augustine Kwame PLoS One Research Article PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron(®) Equinox Cobalt-60 teletherapy machine. METHODS: We examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm × 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle. RESULTS: The estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was ±1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, α = 0.05, n = 11), gantry angle (p = 0.0018, α = 0.05, n = 24), SSD (p = 0.1802, α = 0.05, n = 11) and wedge angle (p = 0.6834, α = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0º), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose. CONCLUSIONS: GafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film. Public Library of Science 2022-08-19 /pmc/articles/PMC9390906/ /pubmed/35984784 http://dx.doi.org/10.1371/journal.pone.0271000 Text en © 2022 Addo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Addo, Daniel Akwei
Kaufmann, Elsie Effah
Tagoe, Samuel Nii
Kyere, Augustine Kwame
Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title_full Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title_fullStr Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title_full_unstemmed Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title_short Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
title_sort characterization of gafchromic ebt2 film dose measurements using a tissue-equivalent water phantom for a theratron(®) equinox cobalt-60 teletherapy machine
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390906/
https://www.ncbi.nlm.nih.gov/pubmed/35984784
http://dx.doi.org/10.1371/journal.pone.0271000
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