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Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine
PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the sim...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390906/ https://www.ncbi.nlm.nih.gov/pubmed/35984784 http://dx.doi.org/10.1371/journal.pone.0271000 |
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author | Addo, Daniel Akwei Kaufmann, Elsie Effah Tagoe, Samuel Nii Kyere, Augustine Kwame |
author_facet | Addo, Daniel Akwei Kaufmann, Elsie Effah Tagoe, Samuel Nii Kyere, Augustine Kwame |
author_sort | Addo, Daniel Akwei |
collection | PubMed |
description | PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron(®) Equinox Cobalt-60 teletherapy machine. METHODS: We examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm × 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle. RESULTS: The estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was ±1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, α = 0.05, n = 11), gantry angle (p = 0.0018, α = 0.05, n = 24), SSD (p = 0.1802, α = 0.05, n = 11) and wedge angle (p = 0.6834, α = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0º), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose. CONCLUSIONS: GafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film. |
format | Online Article Text |
id | pubmed-9390906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-93909062022-08-20 Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine Addo, Daniel Akwei Kaufmann, Elsie Effah Tagoe, Samuel Nii Kyere, Augustine Kwame PLoS One Research Article PURPOSE: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron(®) Equinox Cobalt-60 teletherapy machine. METHODS: We examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm × 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle. RESULTS: The estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was ±1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, α = 0.05, n = 11), gantry angle (p = 0.0018, α = 0.05, n = 24), SSD (p = 0.1802, α = 0.05, n = 11) and wedge angle (p = 0.6834, α = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0º), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose. CONCLUSIONS: GafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film. Public Library of Science 2022-08-19 /pmc/articles/PMC9390906/ /pubmed/35984784 http://dx.doi.org/10.1371/journal.pone.0271000 Text en © 2022 Addo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Addo, Daniel Akwei Kaufmann, Elsie Effah Tagoe, Samuel Nii Kyere, Augustine Kwame Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title | Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title_full | Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title_fullStr | Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title_full_unstemmed | Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title_short | Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(®) Equinox Cobalt-60 teletherapy machine |
title_sort | characterization of gafchromic ebt2 film dose measurements using a tissue-equivalent water phantom for a theratron(®) equinox cobalt-60 teletherapy machine |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390906/ https://www.ncbi.nlm.nih.gov/pubmed/35984784 http://dx.doi.org/10.1371/journal.pone.0271000 |
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