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Postmenopausal Tubular Adenoma of the Breast: A Case Report
Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of prolifera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390948/ https://www.ncbi.nlm.nih.gov/pubmed/36000143 http://dx.doi.org/10.7759/cureus.27076 |
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author | Miles, Brittany Zeinoddini, Atefeh Lahiji, Arian P Eyzaguirre, Eduardo Nguyen, Quan D |
author_facet | Miles, Brittany Zeinoddini, Atefeh Lahiji, Arian P Eyzaguirre, Eduardo Nguyen, Quan D |
author_sort | Miles, Brittany |
collection | PubMed |
description | Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of proliferative breast lesions from fibroadenomas, which are predominantly stromal. The majority of TAs are found in premenopausal women and the reason for this demographic predilection is not yet known. It is generally not possible to distinguish between TA and other, higher-risk breast lesions prior to biopsy or resection because the clinical and radiographic findings overlap. In this article, we present the case of a TA in a postmenopausal patient and review the epidemiology, histology, carcinogenic potential, and management of such lesions. |
format | Online Article Text |
id | pubmed-9390948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-93909482022-08-22 Postmenopausal Tubular Adenoma of the Breast: A Case Report Miles, Brittany Zeinoddini, Atefeh Lahiji, Arian P Eyzaguirre, Eduardo Nguyen, Quan D Cureus Pathology Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of proliferative breast lesions from fibroadenomas, which are predominantly stromal. The majority of TAs are found in premenopausal women and the reason for this demographic predilection is not yet known. It is generally not possible to distinguish between TA and other, higher-risk breast lesions prior to biopsy or resection because the clinical and radiographic findings overlap. In this article, we present the case of a TA in a postmenopausal patient and review the epidemiology, histology, carcinogenic potential, and management of such lesions. Cureus 2022-07-20 /pmc/articles/PMC9390948/ /pubmed/36000143 http://dx.doi.org/10.7759/cureus.27076 Text en Copyright © 2022, Miles et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Miles, Brittany Zeinoddini, Atefeh Lahiji, Arian P Eyzaguirre, Eduardo Nguyen, Quan D Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title | Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title_full | Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title_fullStr | Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title_full_unstemmed | Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title_short | Postmenopausal Tubular Adenoma of the Breast: A Case Report |
title_sort | postmenopausal tubular adenoma of the breast: a case report |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390948/ https://www.ncbi.nlm.nih.gov/pubmed/36000143 http://dx.doi.org/10.7759/cureus.27076 |
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