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Postmenopausal Tubular Adenoma of the Breast: A Case Report

Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of prolifera...

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Autores principales: Miles, Brittany, Zeinoddini, Atefeh, Lahiji, Arian P, Eyzaguirre, Eduardo, Nguyen, Quan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390948/
https://www.ncbi.nlm.nih.gov/pubmed/36000143
http://dx.doi.org/10.7759/cureus.27076
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author Miles, Brittany
Zeinoddini, Atefeh
Lahiji, Arian P
Eyzaguirre, Eduardo
Nguyen, Quan D
author_facet Miles, Brittany
Zeinoddini, Atefeh
Lahiji, Arian P
Eyzaguirre, Eduardo
Nguyen, Quan D
author_sort Miles, Brittany
collection PubMed
description Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of proliferative breast lesions from fibroadenomas, which are predominantly stromal. The majority of TAs are found in premenopausal women and the reason for this demographic predilection is not yet known. It is generally not possible to distinguish between TA and other, higher-risk breast lesions prior to biopsy or resection because the clinical and radiographic findings overlap. In this article, we present the case of a TA in a postmenopausal patient and review the epidemiology, histology, carcinogenic potential, and management of such lesions.
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spelling pubmed-93909482022-08-22 Postmenopausal Tubular Adenoma of the Breast: A Case Report Miles, Brittany Zeinoddini, Atefeh Lahiji, Arian P Eyzaguirre, Eduardo Nguyen, Quan D Cureus Pathology Tubular adenoma (TA) of the breast is a rare, benign proliferative breast lesion that is predominantly composed of closely compacted tubules with an inner layer of epithelial cells and an outer layer of myoepithelial cells. They are regarded as residing on the opposite end of a spectrum of proliferative breast lesions from fibroadenomas, which are predominantly stromal. The majority of TAs are found in premenopausal women and the reason for this demographic predilection is not yet known. It is generally not possible to distinguish between TA and other, higher-risk breast lesions prior to biopsy or resection because the clinical and radiographic findings overlap. In this article, we present the case of a TA in a postmenopausal patient and review the epidemiology, histology, carcinogenic potential, and management of such lesions. Cureus 2022-07-20 /pmc/articles/PMC9390948/ /pubmed/36000143 http://dx.doi.org/10.7759/cureus.27076 Text en Copyright © 2022, Miles et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Miles, Brittany
Zeinoddini, Atefeh
Lahiji, Arian P
Eyzaguirre, Eduardo
Nguyen, Quan D
Postmenopausal Tubular Adenoma of the Breast: A Case Report
title Postmenopausal Tubular Adenoma of the Breast: A Case Report
title_full Postmenopausal Tubular Adenoma of the Breast: A Case Report
title_fullStr Postmenopausal Tubular Adenoma of the Breast: A Case Report
title_full_unstemmed Postmenopausal Tubular Adenoma of the Breast: A Case Report
title_short Postmenopausal Tubular Adenoma of the Breast: A Case Report
title_sort postmenopausal tubular adenoma of the breast: a case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390948/
https://www.ncbi.nlm.nih.gov/pubmed/36000143
http://dx.doi.org/10.7759/cureus.27076
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