Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice

The biological determinants of the response to immune checkpoint blockade (ICB) in cancer remain incompletely understood. Little is known about dynamic biological events that underpin therapeutic efficacy due to the inability to frequently sample tumours in patients. Here, we map the transcriptional...

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Detalles Bibliográficos
Autores principales: Zemek, Rachael M., Chin, Wee Loong, Fear, Vanessa S., Wylie, Ben, Casey, Thomas H., Forbes, Cath, Tilsed, Caitlin M., Boon, Louis, Guo, Belinda B., Bosco, Anthony, Forrest, Alistair R. R., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lassmann, Timo, Lesterhuis, W. Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390963/
https://www.ncbi.nlm.nih.gov/pubmed/35986006
http://dx.doi.org/10.1038/s41467-022-32567-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390963/
https://www.ncbi.nlm.nih.gov/pubmed/35986006
http://dx.doi.org/10.1038/s41467-022-32567-8

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