The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis

The pleiotropic benefits of statins may result from their impact on vascular inflammation. The molecular process underlying this phenomenon is not fully elucidated. Here, RNA sequencing designed to investigate gene expression patterns following CD47-SIRPα inhibition identifies a link between statins...

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Detalles Bibliográficos
Autores principales: Jarr, Kai-Uwe, Ye, Jianqin, Kojima, Yoko, Ye, Zhongde, Gao, Hua, Schmid, Sofie, Luo, Lingfeng, Baylis, Richard A., Lotfi, Mozhgan, Lopez, Nicolas, Eberhard, Anne V., Smith, Bryan Ronain, Weissman, Irving L., Maegdefessel, Lars, Leeper, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390974/
https://www.ncbi.nlm.nih.gov/pubmed/35990913
http://dx.doi.org/10.1038/s44161-022-00023-x

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