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Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods

High-throughput proteomic profiling using antibody or aptamer-based affinity reagents is used increasingly in human studies. However, direct analyses to address the relative strengths and weaknesses of these platforms are lacking. We assessed findings from the SomaScan1.3K (N = 1301 reagents), the S...

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Detalles Bibliográficos
Autores principales:	Katz, Daniel H., Robbins, Jeremy M., Deng, Shuliang, Tahir, Usman A., Bick, Alexander G., Pampana, Akhil, Yu, Zhi, Ngo, Debby, Benson, Mark D., Chen, Zsu-Zsu, Cruz, Daniel E., Shen, Dongxiao, Gao, Yan, Bouchard, Claude, Sarzynski, Mark A., Correa, Adolfo, Natarajan, Pradeep, Wilson, James G., Gerszten, Robert E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390994/ https://www.ncbi.nlm.nih.gov/pubmed/35984888 http://dx.doi.org/10.1126/sciadv.abm5164

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