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The evolution of a counter-defense mechanism in a virus constrains its host range

Bacteria use diverse immunity mechanisms to defend themselves against their viral predators, bacteriophages. In turn, phages can acquire counter-defense systems, but it remains unclear how such mechanisms arise and what factors constrain viral evolution. Here, we experimentally evolved T4 phage to o...

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Detalles Bibliográficos
Autores principales: Srikant, Sriram, Guegler, Chantal K, Laub, Michael T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391042/
https://www.ncbi.nlm.nih.gov/pubmed/35924892
http://dx.doi.org/10.7554/eLife.79549

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