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A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria
The alpha-Gal epitope (α-Gal) with the determining element galactose-α1,3-galactose can lead to clinically relevant allergic reactions and rejections in xenotransplantation. These immune reactions can develop because humans are devoid of this carbohydrate due to evolutionary loss of the enzyme α1,3-...
Autores principales: | Kreft, Luisa, Schepers, Aloys, Hils, Miriam, Swiontek, Kyra, Flatley, Andrew, Janowski, Robert, Mirzaei, Mohammadali Khan, Dittmar, Michael, Chakrapani, Neera, Desai, Mahesh S., Eyerich, Stefanie, Deng, Li, Niessing, Dierk, Fischer, Konrad, Feederle, Regina, Blank, Simon, Schmidt-Weber, Carsten B., Hilger, Christiane, Biedermann, Tilo, Ohnmacht, Caspar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391071/ https://www.ncbi.nlm.nih.gov/pubmed/35990627 http://dx.doi.org/10.3389/fimmu.2022.958952 |
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