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A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria

The alpha-Gal epitope (α-Gal) with the determining element galactose-α1,3-galactose can lead to clinically relevant allergic reactions and rejections in xenotransplantation. These immune reactions can develop because humans are devoid of this carbohydrate due to evolutionary loss of the enzyme α1,3-...

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Detalles Bibliográficos
Autores principales: Kreft, Luisa, Schepers, Aloys, Hils, Miriam, Swiontek, Kyra, Flatley, Andrew, Janowski, Robert, Mirzaei, Mohammadali Khan, Dittmar, Michael, Chakrapani, Neera, Desai, Mahesh S., Eyerich, Stefanie, Deng, Li, Niessing, Dierk, Fischer, Konrad, Feederle, Regina, Blank, Simon, Schmidt-Weber, Carsten B., Hilger, Christiane, Biedermann, Tilo, Ohnmacht, Caspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391071/
https://www.ncbi.nlm.nih.gov/pubmed/35990627
http://dx.doi.org/10.3389/fimmu.2022.958952

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