Cargando…

Exploring the Mechanism of Aspirin in the Treatment of Kawasaki Disease Based on Molecular Docking and Molecular Dynamics

PURPOSE: The research aims to investigate the mechanism of action of aspirin in the treatment of Kawasaki disease. METHODS: We predicted the targets of aspirin with the help of the Drugbank and PharmMapper databases, the target genes of Kawasaki disease were mined in the GeneCards and Disgenet datab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Li, Cao, Junfeng, Qiu, Yixin, Fu, Yinyin, Chen, Siyi, He, Mengjia, Chen, Shengyan, Xie, Wei, Yang, Xingyu, Wang, Chaochao, Wu, Mei, Xu, Hengxiang, Chen, Yijun, Zhang, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391120/ https://www.ncbi.nlm.nih.gov/pubmed/35990842 http://dx.doi.org/10.1155/2022/9828518

Ejemplares similares

Exploring the mechanism of action of Xuanfei Baidu granule (XFBD) in the treatment of COVID-19 based on molecular docking and molecular dynamics
por: Xiong, Li, et al.
Publicado: (2022)

Exploring the mechanism of action of dapansutrile in the treatment of gouty arthritis based on molecular docking and molecular dynamics
por: Cao, Jun-Feng, et al.
Publicado: (2022)

Research on the mechanism of berberine in the treatment of COVID-19 pneumonia pulmonary fibrosis using network pharmacology and molecular docking
por: Cao, Junfeng, et al.
Publicado: (2022)

Mechanism of N-0385 blocking SARS-CoV-2 to treat COVID-19 based on molecular docking and molecular dynamics
por: Cao, Jun-Feng, et al.
Publicado: (2022)

Molecular docking analysis of aspirin analogues with β-catenin
por: Selvaraj, Jayaraman, et al.
Publicado: (2020)

Exploring the mechanism of action of licorice in the treatment of COVID-19 through bioinformatics analysis and molecular dynamics simulation
por: Cao, Jun-Feng, et al.
Publicado: (2022)

Effect of different doses of aspirin on the prognosis of Kawasaki disease
por: Wang, Jinxin, et al.
Publicado: (2020)

Molecular docking and molecular dynamics study Lianhua Qingwen granules (LHQW) treats COVID-19 by inhibiting inflammatory response and regulating cell survival
por: Cao, Jun-Feng, et al.
Publicado: (2022)

The underlying regulatory mechanisms of colorectal carcinoma by combining Vitexin and Aspirin: based on systems biology, molecular docking, molecular dynamics simulation, and in vitro study
por: Chen, Dengsheng, et al.
Publicado: (2023)

Molecular modeling and docking analysis of aspirin with pde7b in the context of neuro-inflammation
por: Balasundaram, Arthi, et al.
Publicado: (2020)

The Potential Bioactive Components of Nine TCM Prescriptions Against COVID-19 in Lung Cancer Were Explored Based on Network Pharmacology and Molecular Docking
por: Du, Lin, et al.
Publicado: (2022)

Integration of network pharmacology and molecular docking to explore the molecular mechanism of Cordycepin in the treatment of Alzheimer’s disease
por: Ma, Xiaoying, et al.
Publicado: (2022)

Network Pharmacology, Molecular Docking and Molecular Dynamics to Explore the Potential Immunomodulatory Mechanisms of Deer Antler
por: Liu, Lingyu, et al.
Publicado: (2023)

To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of ischemic stroke by network pharmacology and molecular docking technology
por: Chen, Xingyu, et al.
Publicado: (2021)

Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking
por: Ou, Chen, et al.
Publicado: (2020)

MoDock: A multi-objective strategy improves the accuracy for molecular docking
por: Gu, Junfeng, et al.
Publicado: (2015)

Is High-Dose Aspirin Necessary in the Acute Phase of Kawasaki Disease?
por: Lee, Goni, et al.
Publicado: (2013)

Immature platelets and antiplatelet therapy response to aspirin in Kawasaki disease
por: Pi, Lei, et al.
Publicado: (2018)

Gene Polymorphism of Aspirin-Induced Urticaria in Children With Kawasaki Disease
por: Zhang, Hui, et al.
Publicado: (2019)

Molecular Docking and Virtual Screening of an Influenza Virus Inhibitor That Disrupts Protein–Protein Interactions
por: Ren, Yixin, et al.
Publicado: (2021)

Exploration of Simiao-Yongan Decoction on knee osteoarthritis based on network pharmacology and molecular docking
por: Wang, Ying, et al.
Publicado: (2023)

Exploring the nucleotide molecular mechanism of compound kushen injection for lung adenocarcinoma based on network pharmacology and molecular docking
por: Ye, Zhangpeng, et al.
Publicado: (2022)

Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking
por: Tan, Xiaoqi, et al.
Publicado: (2022)

Exploring the target and molecular mechanism of Astragalus membranaceus in the treatment of vascular cognitive impairment based on network pharmacology and molecular docking
por: Lin, Long, et al.
Publicado: (2023)

Spectrum-Effect Relationship-Based Strategy Combined with Molecular Docking to Explore Bioactive Flavonoids from Sceptridium ternatum
por: Zhu, Junfeng, et al.
Publicado: (2022)

Bridging Molecular Docking to Molecular Dynamics in Exploring Ligand-Protein Recognition Process: An Overview
por: Salmaso, Veronica, et al.
Publicado: (2018)

Molecular mechanisms of endothelial dysfunction in Kawasaki-disease-associated vasculitis
por: Qiu, Yu, et al.
Publicado: (2022)

Exploring the mechanism of Erchen decoction in the treatment of atherosclerosis based on network pharmacology and molecular docking
por: Li, Wenwen, et al.
Publicado: (2023)

Exploring the mechanism of Xiaoqinglong decoction in the treatment of infantile asthma based on network pharmacology and molecular docking
por: Chen, Daman, et al.
Publicado: (2023)

Molecular targets of aspirin and cancer prevention
por: Alfonso, L, et al.
Publicado: (2014)

Exploration of the Molecular Mechanism of Polygonati Rhizoma in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking
por: Zhao, Jinlong, et al.
Publicado: (2022)

Insight into Ginkgo biloba L. Extract on the Improved Spatial Learning and Memory by Chemogenomics Knowledgebase, Molecular Docking, Molecular Dynamics Simulation, and Bioassay Validations
por: Chen, Yan, et al.
Publicado: (2020)

Altered gut microbiota correlated with systemic inflammation in children with Kawasaki disease
por: Chen, Jie, et al.
Publicado: (2020)

A case of rectal ulcers during aspirin therapy in acute Kawasaki disease
por: Han, Yong, et al.
Publicado: (2020)

Molecular Structure-Affinity Relationship of Bufadienolides and Human Serum Albumin In Vitro and Molecular Docking Analysis
por: Zhou, Jing, et al.
Publicado: (2015)

Exploring the mechanism of Buyang Huanwu Decoction in the treatment of spinal cord injury based on network pharmacology and molecular docking
por: Wang, Ying, et al.
Publicado: (2022)

Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
por: Li, Jie, et al.
Publicado: (2018)

Exploring the Antihyperglycemic Chemical Composition and Mechanisms of Tea Using Molecular Docking
por: Sun, Yue, et al.
Publicado: (2020)

Network Pharmacology and Molecular Docking to Explore the Mechanism of Kangxian Decoction for Epilepsy
por: Wang, Weitao, et al.
Publicado: (2022)

Exploring the Mechanism of Curcumin on Retinoblastoma Based on Network Pharmacology and Molecular Docking
por: Wu, Chengfu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4c790r2rlg907ipbdpnhgj5kml