Cargando…

Integrated Serum Metabolomics and Network Pharmacology to Reveal the Interventional Effects of Quzhi Decoction against Osteoarthritis Pain

OBJECTIVES: Chronic pain, the main symptom of knee osteoarthritis (OA), remains the primary reason for decreased functional capacity. Quzhi decoction, a TCM prescription, is effective in treating chronic pain in OA, but the potential mechanisms require further exploration. METHODS: An anterior cruci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Xiaoqing, Wu, Peng, Jie, Lishi, Zhang, Li, Mao, Jun, Yin, Songjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391123/ https://www.ncbi.nlm.nih.gov/pubmed/35992559 http://dx.doi.org/10.1155/2022/9116175

Ejemplares similares

GCTOF-MS Combined LC-QTRAP-MS/MS Reveals Metabolic Difference Between Osteoarthritis and Osteoporotic Osteoarthritis and the Intervention Effect of Erxian Decoction
por: Ma, Zhenyuan, et al.
Publicado: (2022)

Should synovectomy be performed during total knee arthroplasty for knee osteoarthritis: A protocol for systematic review and meta-analysis
por: Li, Mingchao, et al.
Publicado: (2021)

Quzhi Formula Alleviates Nonalcoholic Steatohepatitis by Impairing Hepatocyte Lipid Accumulation and Inflammation via Bip/eIF2α Signaling
por: Wu, Yue-Lan, et al.
Publicado: (2022)

Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction
por: Pan, Boyu, et al.
Publicado: (2022)

Correction to “Integrated Network Pharmacology Analysis and Serum Metabolomics to Reveal the Antimalaria Mechanism of Artesunate”
por: Wang, Feiran, et al.
Publicado: (2022)

Integrated Network Pharmacology Analysis and Serum Metabolomics to Reveal the Anti-malaria Mechanism of Artesunate
por: Wang, Feiran, et al.
Publicado: (2022)

The Interventional Effects of Tubson-2 Decoction on Ovariectomized Rats as Determined by a Combination of Network Pharmacology and Metabolomics
por: Yang, Fan, et al.
Publicado: (2020)

Network pharmacological analysis on the mechanism of Coix seed decoction for osteoarthritis of the knee
por: Qiu, Junjie, et al.
Publicado: (2023)

Integrated serum pharmacochemistry and metabolomics reveal potential effective components and mechanisms of Shengjiang Xiexin decoction in the treatment of Clostridium difficile infection
por: Cui, Yutao, et al.
Publicado: (2023)

Integrated Network and Experimental Pharmacology for Deciphering the Medicinal Substances and Multiple Mechanisms of Duhuo Jisheng Decoction in Osteoarthritis Therapy
por: Xiao, Wenyu, et al.
Publicado: (2020)

Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation
por: Chen, Yan, et al.
Publicado: (2023)

Integrating Network Pharmacology and Metabolomics to Elucidate the Mechanism of Action of Huang Qin Decoction for Treament of Diabetic Liver Injury
por: Xu, Xiaomin, et al.
Publicado: (2022)

Network Pharmacology Identifies the Mechanisms of Action of Shaoyao Gancao Decoction in the Treatment of Osteoarthritis
por: Zhu, Naiqiang, et al.
Publicado: (2019)

Integrating Network Analysis and Metabolomics to Reveal Mechanism of Huaganjian Decoction in Treatment of Cholestatic Hepatic Injury
por: Dong, Qin, et al.
Publicado: (2022)

Ganghuo Kanggan Decoction in Influenza: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Lai, Yanni, et al.
Publicado: (2020)

Serum and brain metabolomic study reveals the protective effects of Bai-Mi-Decoction on rats with ischemic stroke
por: Yang, Lingling, et al.
Publicado: (2022)

Integrated Metabonomics and Network Pharmacology to Reveal the Action Mechanism Effect of Shaoyao Decoction on Ulcerative Colitis
por: Wu, Jin, et al.
Publicado: (2022)

Exploration of Simiao-Yongan Decoction on knee osteoarthritis based on network pharmacology and molecular docking
por: Wang, Ying, et al.
Publicado: (2023)

Deciphering the Metabolomics-Based Intervention of Yanghe Decoction on Hashimoto's Thyroiditis
por: Zhang, Xing, et al.
Publicado: (2022)

Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Guo, Qingqing, et al.
Publicado: (2017)

Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model: In Vitro Pharmacology and Cell Metabolomics
por: Yin, Fengxia, et al.
Publicado: (2022)

Mechanism of Modified Danggui Sini Decoction for Knee Osteoarthritis Based on Network Pharmacology and Molecular Docking
por: Feng, Chaoqun, et al.
Publicado: (2021)

Analysis of Antidepressant Activity of Huang-Lian Jie-Du Decoction Through Network Pharmacology and Metabolomics
por: Qu, Shu-Yue, et al.
Publicado: (2021)

Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics
por: Cao, Yong-Jun, et al.
Publicado: (2022)

Network Pharmacology Prediction and Pharmacological Verification Mechanism of Yeju Jiangya Decoction on Hypertension
por: Wang, Ting, et al.
Publicado: (2021)

The Mechanisms of Sijunzi Decoction in the Treatment of Chronic Gastritis Revealed by Network Pharmacology
por: Wang, Ting, et al.
Publicado: (2020)

Network Pharmacology Integrated Molecular Docking Revealed the Mechanism of Jianpi Yiqi Taohua Decoction Against Ulcerative Colitis
por: Jia, Lin, et al.
Publicado: (2022)

Integrated Pharmacology Reveals the Molecular Mechanism of Gegen Qinlian Decoction Against Lipopolysaccharide-induced Acute Lung Injury
por: Li, Wei, et al.
Publicado: (2022)

Integrated network pharmacology and proteomics to reveal the cognitive improvement effect of Wuzang Wenyang Huayu decoction on vascular dementia
por: Sun, Yuhao, et al.
Publicado: (2022)

Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritis
por: ZHENG, CHUN-SONG, et al.
Publicado: (2013)

Discussion on the molecular mechanism of Duhuo Jisheng decoction in treating osteoarthritis based on network pharmacology and molecular docking
por: Yang, Liu, et al.
Publicado: (2022)

Analyzing network pharmacology and molecular docking to clarify Duhuo Jisheng decoction potential mechanism of osteoarthritis mitigation
por: Cui, Zhenhai, et al.
Publicado: (2022)

Integrated Serum Pharmacochemistry, Metabolomics, and Network Pharmacology to Reveal the Material Basis and Mechanism of Danggui Shaoyao San in the Treatment of Primary Dysmenorrhea
por: Xiong, Hui, et al.
Publicado: (2022)

Integrated transcriptomic and metabolomic profiles reveal the protective mechanism of modified Danggui Buxue decoction on radiation-induced leukopenia in mice
por: Chen, Wei, et al.
Publicado: (2023)

Mechanism of SQQX Decoction's Protective Effect on SHR: A Serum Metabolomics-Based Analysis
por: Wu, Jiayun, et al.
Publicado: (2020)

The Pharmacology of Pain Associated With the Monoiodoacetate Model of Osteoarthritis
por: de Sousa Valente, João
Publicado: (2019)

Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Chongcaoyishen Decoction Against Chronic Kidney Disease
por: Fan, Zhenliang, et al.
Publicado: (2022)

Urinary Metabolomics Study of the Intervention Effect of Hypoglycemic Decoction on Type 2 Diabetes Mellitus Rats Model
por: Pan, Lin-Lin, et al.
Publicado: (2019)

Integrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome
por: Ding, Jie, et al.
Publicado: (2022)

Network-Based Pharmacological Study on the Mechanism of Guishao-Liujun Decoction in the Treatment of Gastric Cancer
por: Qian, Xiaoqing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9e1bcvar1jim834iikll8aqtst