Cargando…
A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391170/ https://www.ncbi.nlm.nih.gov/pubmed/35990251 http://dx.doi.org/10.1155/2022/7593750 |
_version_ | 1784770813435576320 |
---|---|
author | Xu, He Zheng, Qunli Zhu, Jingshu Xie, Zuoling Cheng, Haitao Li, Peng Ji, Yimu |
author_facet | Xu, He Zheng, Qunli Zhu, Jingshu Xie, Zuoling Cheng, Haitao Li, Peng Ji, Yimu |
author_sort | Xu, He |
collection | PubMed |
description | The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and a disease prediction model is constructed. The model initially constructs the relationship graph between the physical indicator and the test value based on the normal range of human physical examination index. And the human physical examination index for testing value by knowledge representation learning model is encoded. Then, the patient physical examination data is represented as a vector and input into a deep learning model built with self-attention mechanism and convolutional neural network to implement disease prediction. The experimental results show that the model which is used in diabetes prediction yields an accuracy of 97.18% and the recall of 87.55%, which outperforms other machine learning methods (e.g., lasso, ridge, support vector machine, random forest, and XGBoost). Compared with the best performing random forest method, the recall is increased by 5.34%, respectively. Therefore, it can be concluded that the application of medical knowledge into deep learning through knowledge representation learning can be used in diabetes prediction for the purpose of early detection and assisting diagnosis. |
format | Online Article Text |
id | pubmed-9391170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93911702022-08-20 A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction Xu, He Zheng, Qunli Zhu, Jingshu Xie, Zuoling Cheng, Haitao Li, Peng Ji, Yimu Dis Markers Research Article The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and a disease prediction model is constructed. The model initially constructs the relationship graph between the physical indicator and the test value based on the normal range of human physical examination index. And the human physical examination index for testing value by knowledge representation learning model is encoded. Then, the patient physical examination data is represented as a vector and input into a deep learning model built with self-attention mechanism and convolutional neural network to implement disease prediction. The experimental results show that the model which is used in diabetes prediction yields an accuracy of 97.18% and the recall of 87.55%, which outperforms other machine learning methods (e.g., lasso, ridge, support vector machine, random forest, and XGBoost). Compared with the best performing random forest method, the recall is increased by 5.34%, respectively. Therefore, it can be concluded that the application of medical knowledge into deep learning through knowledge representation learning can be used in diabetes prediction for the purpose of early detection and assisting diagnosis. Hindawi 2022-08-12 /pmc/articles/PMC9391170/ /pubmed/35990251 http://dx.doi.org/10.1155/2022/7593750 Text en Copyright © 2022 He Xu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Xu, He Zheng, Qunli Zhu, Jingshu Xie, Zuoling Cheng, Haitao Li, Peng Ji, Yimu A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title | A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title_full | A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title_fullStr | A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title_full_unstemmed | A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title_short | A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction |
title_sort | deep learning model incorporating knowledge representation vectors and its application in diabetes prediction |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391170/ https://www.ncbi.nlm.nih.gov/pubmed/35990251 http://dx.doi.org/10.1155/2022/7593750 |
work_keys_str_mv | AT xuhe adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT zhengqunli adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT zhujingshu adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT xiezuoling adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT chenghaitao adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT lipeng adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT jiyimu adeeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT xuhe deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT zhengqunli deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT zhujingshu deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT xiezuoling deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT chenghaitao deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT lipeng deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction AT jiyimu deeplearningmodelincorporatingknowledgerepresentationvectorsanditsapplicationindiabetesprediction |