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A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction

The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and...

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Autores principales: Xu, He, Zheng, Qunli, Zhu, Jingshu, Xie, Zuoling, Cheng, Haitao, Li, Peng, Ji, Yimu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391170/
https://www.ncbi.nlm.nih.gov/pubmed/35990251
http://dx.doi.org/10.1155/2022/7593750
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author Xu, He
Zheng, Qunli
Zhu, Jingshu
Xie, Zuoling
Cheng, Haitao
Li, Peng
Ji, Yimu
author_facet Xu, He
Zheng, Qunli
Zhu, Jingshu
Xie, Zuoling
Cheng, Haitao
Li, Peng
Ji, Yimu
author_sort Xu, He
collection PubMed
description The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and a disease prediction model is constructed. The model initially constructs the relationship graph between the physical indicator and the test value based on the normal range of human physical examination index. And the human physical examination index for testing value by knowledge representation learning model is encoded. Then, the patient physical examination data is represented as a vector and input into a deep learning model built with self-attention mechanism and convolutional neural network to implement disease prediction. The experimental results show that the model which is used in diabetes prediction yields an accuracy of 97.18% and the recall of 87.55%, which outperforms other machine learning methods (e.g., lasso, ridge, support vector machine, random forest, and XGBoost). Compared with the best performing random forest method, the recall is increased by 5.34%, respectively. Therefore, it can be concluded that the application of medical knowledge into deep learning through knowledge representation learning can be used in diabetes prediction for the purpose of early detection and assisting diagnosis.
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spelling pubmed-93911702022-08-20 A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction Xu, He Zheng, Qunli Zhu, Jingshu Xie, Zuoling Cheng, Haitao Li, Peng Ji, Yimu Dis Markers Research Article The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and a disease prediction model is constructed. The model initially constructs the relationship graph between the physical indicator and the test value based on the normal range of human physical examination index. And the human physical examination index for testing value by knowledge representation learning model is encoded. Then, the patient physical examination data is represented as a vector and input into a deep learning model built with self-attention mechanism and convolutional neural network to implement disease prediction. The experimental results show that the model which is used in diabetes prediction yields an accuracy of 97.18% and the recall of 87.55%, which outperforms other machine learning methods (e.g., lasso, ridge, support vector machine, random forest, and XGBoost). Compared with the best performing random forest method, the recall is increased by 5.34%, respectively. Therefore, it can be concluded that the application of medical knowledge into deep learning through knowledge representation learning can be used in diabetes prediction for the purpose of early detection and assisting diagnosis. Hindawi 2022-08-12 /pmc/articles/PMC9391170/ /pubmed/35990251 http://dx.doi.org/10.1155/2022/7593750 Text en Copyright © 2022 He Xu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Xu, He
Zheng, Qunli
Zhu, Jingshu
Xie, Zuoling
Cheng, Haitao
Li, Peng
Ji, Yimu
A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title_full A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title_fullStr A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title_full_unstemmed A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title_short A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction
title_sort deep learning model incorporating knowledge representation vectors and its application in diabetes prediction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391170/
https://www.ncbi.nlm.nih.gov/pubmed/35990251
http://dx.doi.org/10.1155/2022/7593750
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