Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nanoparticle-enhanced immunoassay read by dark-field microscopy that detects two Mycobacterium...

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Detalles Bibliográficos
Autores principales: Zheng, Wenshu, LaCourse, Sylvia M., Song, Bofan, Singh, Dhiraj Kumar, Khanna, Mayank, Olivo, Juan, Stern, Joshua, Escudero, Jaclyn N., Vergara, Carlos, Zhang, Fangfang, Li, Shaobai, Wang, Shu, Cranmer, Lisa M., Huang, Zhen, Bojanowski, Christine M., Bao, Duran, Njuguna, Irene, Xiao, Yating, Wamalwa, Dalton C., Nguyen, Duc T., Yang, Li, Maleche-Obimbo, Elizabeth, Nguyen, Nhung, Zhang, Lili, Phan, Ha, Fan, Jia, Ning, Bo, Li, Chenzhong, Lyon, Christopher J., Graviss, Edward A., John-Stewart, Grace, Mitchell, Charles D., Ramsay, Alistair J., Kaushal, Deepak, Liang, Rongguang, Pérez-Then, Eddy, Hu, Tony Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391224/
https://www.ncbi.nlm.nih.gov/pubmed/35986185
http://dx.doi.org/10.1038/s41551-022-00922-1

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