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Ultrasound-Induced Release of Nimodipine from Drug-Loaded Block Copolymer Micelles: In Vivo Analysis
Nimodipine prevents cerebral vasospasm and improves functional outcome after aneurysmal subarachnoid hemorrhage (aSAH). The beneficial effect is limited by low oral bioavailability of nimodipine, which resulted in an increasing use of nanocarriers with sustained intrathecal drug release in order to...
Autores principales: | Döring, Katja, Sperling, Swetlana, Ninkovic, Milena, Schroeder, Henning, Fischer, André, Stadelmann, Christine, Streit, Frank, Binder, Lutz, Mielke, Dorothee, Rohde, Veit, Malinova, Vesna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391244/ https://www.ncbi.nlm.nih.gov/pubmed/34988870 http://dx.doi.org/10.1007/s12975-021-00979-1 |
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