Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

BACKGROUND: Positron emission tomography (PET) imaging in early Parkinson's disease (PD) subjects reveals that increased dopamine (DA) turnover and reduced dopamine transporter (DAT) density precede decreases in DA synthesis and storage. The rat α‐synuclein preformed fibril (α‐syn PFF) model pr...

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Detalles Bibliográficos
Autores principales: Sossi, Vesna, Patterson, Joseph R., McCormick, Siobhan, Kemp, Christopher J., Miller, Kathryn M., Stoll, Anna C., Kuhn, Nathan, Kubik, Michael, Kochmanski, Joseph, Luk, Kelvin C., Sortwell, Caryl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391270/
https://www.ncbi.nlm.nih.gov/pubmed/35524682
http://dx.doi.org/10.1002/mds.29051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391270/
https://www.ncbi.nlm.nih.gov/pubmed/35524682
http://dx.doi.org/10.1002/mds.29051

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